Current Overview on Clinical Management of Chronic Constipation.
chronic constipation
clinical management
constipation
pharmacology
surgery
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
16 Apr 2021
16 Apr 2021
Historique:
received:
22
02
2021
revised:
09
04
2021
accepted:
13
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
1
5
2021
Statut:
epublish
Résumé
Constipation is one of the major gastrointestinal disorders diagnosed in clinical practice in Western countries. Almost 20% of population suffer from this disorder, which means constipation is a substantial utilization of healthcare. Pathophysiology of constipation is complex and multifactorial, where aspects like disturbance in colonic transit, genetic predisposition, lifestyle habits, psychological distress, and many others need to be taken into consideration. Diagnosis of constipation is troublesome and requires thorough accurate examination. A nonpharmacological approach, education of the patient about the importance of lifestyle changes like diet and sport activity state, are the first line of therapy. In case of ineffective treatment, pharmacological treatments such as laxatives, secretagogues, serotonergic agonists, and many other medications should be induced. If pharmacologic treatment fails, the definitive solution for constipation might be surgical approach. Commonness of this disorder, costs of medical care and decrease in quality life cause constipation is a serious issue for many specialists. The aim of this review is to present current knowledge of chronic constipation and management of this disorder.
Identifiants
pubmed: 33923772
pii: jcm10081738
doi: 10.3390/jcm10081738
pmc: PMC8073140
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Narodowe Centrum Nauki
ID : 504/5-120-02/504-11-014, to JW
Organisme : Medical University of Lodz
ID : 503/1-156-04/503-11-001-19-00, to JF
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