The Heterogeneity of Skewness in T2W-Based Radiomics Predicts the Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer.

MRI radiomics rectal cancer

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
28 Apr 2021
Historique:
received: 18 03 2021
revised: 23 04 2021
accepted: 24 04 2021
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 1 5 2021
Statut: epublish

Résumé

Our study aimed to investigate whether radiomics on MRI sequences can differentiate responder (R) and non-responder (NR) patients based on the tumour regression grade (TRG) assigned after surgical resection in locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (nCRT). Eighty-five patients undergoing primary staging with MRI were retrospectively evaluated, and 40 patients were finally selected. The ROIs were manually outlined in the tumour site on T2w sequences in the oblique-axial plane. Based on the TRG, patients were grouped as having either a complete or a partial response (TRG = (0,1),

Identifiants

pubmed: 33924854
pii: diagnostics11050795
doi: 10.3390/diagnostics11050795
pmc: PMC8146691
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Francesca Coppola (F)

Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.
SIRM Foundation, Italian Society of Medical and Interventional Radiology, Via della Signora 2, 20122 Milan, Italy.

Margherita Mottola (M)

Advanced Research Center on Electronic Systems (ARCES), University of Bologna, Via Toffano 2/2, 40125 Bologna, Italy.

Silvia Lo Monaco (S)

Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.

Arrigo Cattabriga (A)

Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.

Maria Adriana Cocozza (MA)

Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.

Jia Cheng Yuan (JC)

Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.

Caterina De Benedittis (C)

Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.

Dajana Cuicchi (D)

Medical and Surgical Department of Digestive, Hepatic and Endocrine-Metabolic Diseases, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138 Bologna, Italy.

Alessandra Guido (A)

Department of Radiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138 Bologna, Italy.

Fabiola Lorena Rojas Llimpe (FL)

Division of Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.

Antonietta D'Errico (A)

Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138 Bologna, Italy.

Andrea Ardizzoni (A)

Division of Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.

Gilberto Poggioli (G)

Medical and Surgical Department of Digestive, Hepatic and Endocrine-Metabolic Diseases, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138 Bologna, Italy.

Lidia Strigari (L)

Department of Medical Physics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, S. Orsola-Malpighi Hospital, 40138 Bologna, Italy.

Alessio Giuseppe Morganti (AG)

Department of Radiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138 Bologna, Italy.

Franco Bazzoli (F)

Department of Medical and Surgical Sciences, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138 Bologna, Italy.

Luigi Ricciardiello (L)

Department of Medical and Surgical Sciences, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138 Bologna, Italy.

Rita Golfieri (R)

Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni 15, 40138 Bologna, Italy.

Alessandro Bevilacqua (A)

Advanced Research Center on Electronic Systems (ARCES), University of Bologna, Via Toffano 2/2, 40125 Bologna, Italy.
Department of Computer Science and Engineering, University of Bologna, Viale Risorgimento 2, 40136 Bologna, Italy.

Classifications MeSH