The Role of Lung Colonization in Connective Tissue Disease-Associated Interstitial Lung Disease.
autoimmune disease
connective tissue diseases
high-resolution computed tomography
interstitial lung diseases
lung function tests
microbiota
pulmonary fibrosis
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
27 Apr 2021
27 Apr 2021
Historique:
received:
24
03
2021
revised:
15
04
2021
accepted:
21
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
1
5
2021
Statut:
epublish
Résumé
Connective tissue diseases (CTDs) may frequently manifest with interstitial lung disease (ILD), which may severely impair quality and expectation of life. CTD-ILD generally has a chronic clinical course, with possible acute exacerbations. Although several lines of evidence indicate a relevant role of infections in the acute exacerbations of CTD-ILD, little information is available regarding the prevalence of infections in chronic CTD-ILD and their possible role in the clinical course. The aim of the present retrospective study was the identification of lung microbial colonization in broncho-alveolar lavage from patients affected by stable CTD-ILD with radiologically defined lung involvement. We demonstrated that 22.7% of patients with CTD-ILD display microbial colonization by
Identifiants
pubmed: 33925354
pii: microorganisms9050932
doi: 10.3390/microorganisms9050932
pmc: PMC8146539
pii:
doi:
Types de publication
Journal Article
Langues
eng
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