Alpha
Aged
Anti-Inflammatory Agents
/ therapeutic use
Bronchodilator Agents
/ therapeutic use
Dyspnea
/ surgery
Endoscopy
Female
Forced Expiratory Volume
Humans
Lung
Male
Middle Aged
Oxygen
/ therapeutic use
Pneumonectomy
/ adverse effects
Prognosis
Pulmonary Disease, Chronic Obstructive
/ complications
Pulmonary Emphysema
/ complications
Risk
Smoking
/ adverse effects
Smoking Cessation
Time Factors
alpha 1-Antitrypsin
/ metabolism
alpha 1-Antitrypsin Deficiency
/ complications
AATD-related pulmonary emphysema
Alpha(1)-antitrypsin deficiency
Chronic obstructive pulmonary disease
Endobronchial lung volume reduction
Lung volume reduction surgery
Journal
Thoracic surgery clinics
ISSN: 1558-5069
Titre abrégé: Thorac Surg Clin
Pays: United States
ID NLM: 101198195
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
2
7
2021
Statut:
ppublish
Résumé
Chronic obstructive pulmonary usually is subcategorized into 2 groups: chronic bronchitis and emphysema. The main cause of chronic bronchitis and emphysema is smoking; however, alpha1-antitrypsin also has been seen to cause emphysema in patients who are deficient. As symptoms and lung function decline, treatment modalities, such as lung volume reduction surgery, have been used in individuals with chronic obstructive pulmonary disease and upper lobe predominant emphysema. This article analyzes multiple published series where lung volume reduction surgery has been used in individuals with alpha1-antitrypsin deficiency and their overall outcomes.
Identifiants
pubmed: 33926668
pii: S1547-4127(21)00006-2
doi: 10.1016/j.thorsurg.2021.02.002
pii:
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Bronchodilator Agents
0
SERPINA1 protein, human
0
alpha 1-Antitrypsin
0
Oxygen
S88TT14065
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
139-160Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.