Effect of pulmonary hypertension on exercise tolerance in patients with COPD: a prognostic systematic review and meta-analysis.

Exercise Test Exercise Tolerance Humans Hypertension, Pulmonary / diagnosis Prognosis Pulmonary Disease, Chronic Obstructive / diagnosis

Journal

European respiratory review : an official journal of the European Respiratory Society
ISSN: 1600-0617
Titre abrégé: Eur Respir Rev
Pays: England
ID NLM: 9111391

Informations de publication

Date de publication:
30 Jun 2021
Historique:
received: 03 10 2020
accepted: 17 12 2020
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 25 11 2021
Statut: epublish

Résumé

Pulmonary hypertension (PH) is a frequent complication in patients with COPD. To determine if, in patients with COPD, the presence of PH decreases exercise tolerance. We included studies that analysed exercise tolerance using a cardiopulmonary exercise test (CPET) in patients with COPD with PH (COPD-PH) and without PH (COPD-nonPH). Two independent reviewers analysed the studies, extracted the data and assessed the quality of the evidence. Of the 4915 articles initially identified, seven reported 257 patients with COPD-PH and 404 patients with COPD-nonPH. The COPD-PH group showed differences in peak oxygen consumption ( Exercise tolerance was significantly lower in patients with COPD-PH than in patients with COPD-nonPH, particularly in nontransplant candidates.

Sections du résumé

BACKGROUND BACKGROUND
Pulmonary hypertension (PH) is a frequent complication in patients with COPD.
OBJECTIVE OBJECTIVE
To determine if, in patients with COPD, the presence of PH decreases exercise tolerance.
METHODS METHODS
We included studies that analysed exercise tolerance using a cardiopulmonary exercise test (CPET) in patients with COPD with PH (COPD-PH) and without PH (COPD-nonPH). Two independent reviewers analysed the studies, extracted the data and assessed the quality of the evidence.
RESULTS RESULTS
Of the 4915 articles initially identified, seven reported 257 patients with COPD-PH and 404 patients with COPD-nonPH. The COPD-PH group showed differences in peak oxygen consumption (
CONCLUSION CONCLUSIONS
Exercise tolerance was significantly lower in patients with COPD-PH than in patients with COPD-nonPH, particularly in nontransplant candidates.

Identifiants

DOI: 10.1183/16000617.0321-2020 PMID: 33927006 PMC: PMC9489125
pubmed: 33927006
pii: 30/160/200321
doi: 10.1183/16000617.0321-2020
pmc: PMC9489125
pii:
doi:

Types de publication

Journal Article Meta-Analysis Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright ©The authors 2021.

Déclaration de conflit d'intérêts

Conflict of interest: R. Torres-Castro has nothing to disclose. Conflict of interest: E. Gimeno-Santos has nothing to disclose. Conflict of interest: J. Vilaró has nothing to disclose. Conflict of interest: M. Roqué-Figuls has nothing to disclose. Conflict of interest: J. Moisés has nothing to disclose. Conflict of interest: L. Vasconcello-Castillo has nothing to disclose. Conflict of interest: T. Orizaga has nothing to disclose. Conflict of interest: J.A. Barberà has nothing to disclose. Conflict of interest: I. Blanco has nothing to disclose.

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Auteurs

Rodrigo Torres-Castro (R)

Dept of Pulmonary Medicine, Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Dept of Physical Therapy, Faculty of Medicine, University of Chile, Santiago, Chile.
ORCID: 0000-0001-7974-4333

Elena Gimeno-Santos (E)

Dept of Pulmonary Medicine, Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain.
ORCID: 0000-0001-5149-2015

Jordi Vilaró (J)

Blanquerna School of Health Sciences, Global Research on Wellbeing (GRoW), Universitat Ramon Llull, Barcelona, Spain.
ORCID: 0000-0002-2150-8992

Marta Roqué-Figuls (M)

Iberoamerican Cochrane Centre - Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain.
CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
ORCID: 0000-0003-0043-1364

Jorge Moisés (J)

Dept of Pulmonary Medicine, Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Biomedical Research Networking Center on Respiratory Diseases (CIBERES), Madrid, Spain.
ORCID: 0000-0001-9504-7511

Luis Vasconcello-Castillo (L)

Dept of Physical Therapy, Faculty of Medicine, University of Chile, Santiago, Chile.

Tanya Orizaga (T)

Dept of Pulmonary Medicine, Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

Joan Albert Barberà (JA)

Dept of Pulmonary Medicine, Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Biomedical Research Networking Center on Respiratory Diseases (CIBERES), Madrid, Spain.
Contributed equally as senior authors.
ORCID: 0000-0003-1469-4990

Isabel Blanco (I)

Dept of Pulmonary Medicine, Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain iblanco2@clinic.cat.
Biomedical Research Networking Center on Respiratory Diseases (CIBERES), Madrid, Spain.
Contributed equally as senior authors.
ORCID: 0000-0001-9452-3432

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Ergométrie › Épreuve d'effort › Effect of pulmonary hypertension on exercise...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Tolérance à l'effort › Effect of pulmonary hypertension on exercise...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Effect of pulmonary hypertension on exercise...
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Hypertension artérielle › Hypertension pulmonaire › Effect of pulmonary hypertension on exercise...
questionsmedicales.fr › Diagnostic › Pronostic › Effect of pulmonary hypertension on exercise...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Broncho-pneumopathie chronique obstructive › Effect of pulmonary hypertension on exercise...