Small crystals with severe consequences.
Journal
Journal of surgical case reports
ISSN: 2042-8812
Titre abrégé: J Surg Case Rep
Pays: England
ID NLM: 101560169
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
27
02
2021
accepted:
17
03
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
1
5
2021
Statut:
epublish
Résumé
We present the case of a 23-year-old patient who developed a severe gastric ischemia after the ingestion of a single dose of sodium polystyrene sulfonate (SPS) orally. Emergency surgery confirmed extensive full thickness gastric necrosis, prompting a total gastrectomy. Histopathology showed kayexalate crystals in the gastric wall, suggesting SPS-related ischemic gastritis. After radical resection of the affected stomach, this young patient was able to fully recover. Although effective, the widespread use of SPS to treat hyperpotassemia remains a debated topic because of rare but serious adverse events like the forming of kayexalate crystal residues in the gastrointestinal tract. These crystal residues are mostly found in the large intestine and can lead to ulceration and necrosis. Physicians need to be aware of this rare but potentially devastating adverse effect of SPS ingestion.
Identifiants
pubmed: 33927869
doi: 10.1093/jscr/rjab135
pii: rjab135
pmc: PMC8068420
doi:
Types de publication
Case Reports
Langues
eng
Pagination
rjab135Informations de copyright
Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2021.
Références
Am J Kidney Dis. 2012 Sep;60(3):409-16
pubmed: 22683337
Rev Assoc Med Bras (1992). 2018 Aug;64(8):680-683
pubmed: 30673037
Clinics (Sao Paulo). 2015 Jul;70(7):515-23
pubmed: 26222822
Am J Med. 2013 Mar;126(3):264.e9-24
pubmed: 23321430
Biol Blood Marrow Transplant. 2016 Apr;22(4):605-616
pubmed: 26409924
Haematologica. 2018 Oct;103(10):1708-1719
pubmed: 30076185
Anticancer Res. 2017 Apr;37(4):1547-1555
pubmed: 28373413
Ann Pharmacother. 2016 Jun;50(6):455-62
pubmed: 27048188
Nephrol Dial Transplant. 2012 Dec;27(12):4294-7
pubmed: 22989741
Am J Kidney Dis. 1986 Nov;8(5):323-31
pubmed: 3538856
J Am Soc Nephrol. 2010 May;21(5):733-5
pubmed: 20167700
Am J Surg Pathol. 2001 May;25(5):637-44
pubmed: 11342776
Gastroenterol Rep (Oxf). 2014 Aug;2(3):235-6
pubmed: 24759345
Clin Radiol. 2014 Nov;69(11):e445-9
pubmed: 25219954
Kaohsiung J Med Sci. 2011 Apr;27(4):155-8
pubmed: 21463839