Rostro-caudal different energy metabolism leading to differences in degeneration in spinal cord injury.

ATP degeneration glycolysis metabolism oxidative stress

Journal

Brain communications
ISSN: 2632-1297
Titre abrégé: Brain Commun
Pays: England
ID NLM: 101755125

Informations de publication

Date de publication:
2021
Historique:
received: 29 09 2020
revised: 12 02 2021
accepted: 19 02 2021
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 1 5 2021
Statut: epublish

Résumé

Spinal cord injury gradually spreads away from the epicentre of injury. The rate of degeneration on the rostral side of the injury differs from that on the caudal side. Rostral degeneration is an immediate process, while caudal degeneration is delayed. In this study, we demonstrated that the rostro-caudal differences in energy metabolism led to differences in the spread of degeneration in early thoracic cord injury using

Identifiants

pubmed: 33928249
doi: 10.1093/braincomms/fcab058
pii: fcab058
pmc: PMC8066884
doi:

Types de publication

Journal Article

Langues

eng

Pagination

fcab058

Informations de copyright

© The Author(s) (2021). Published by Oxford University Press on behalf of the Guarantors of Brain.

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Auteurs

Yuichiro Ohnishi (Y)

Department of Neurosurgery, Osaka University Medical School, Osaka, Japan.
Department of Research Promotion and Management, National Cerebral and Cardiovascular Center, Osaka, Japan.

Masamichi Yamamoto (M)

Department of Research Promotion and Management, National Cerebral and Cardiovascular Center, Osaka, Japan.

Yuki Sugiura (Y)

Department of Biochemistry, Keio University School of Medicine, Tokyo, Japan.

Daiki Setoyama (D)

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Haruhiko Kishima (H)

Department of Research Promotion and Management, National Cerebral and Cardiovascular Center, Osaka, Japan.

Classifications MeSH