ImmunoCluster computational biology cytometry framework human immune monitoring immunology inflammation systems biology

Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
30 04 2021
Historique:
received: 08 09 2020
accepted: 22 04 2021
pubmed: 1 5 2021
medline: 23 11 2021
entrez: 30 4 2021
Statut: epublish

Résumé

High-dimensional cytometry is an innovative tool for immune monitoring in health and disease, and it has provided novel insight into the underlying biology as well as biomarkers for a variety of diseases. However, the analysis of large multiparametric datasets usually requires specialist computational knowledge. Here, we describe

Identifiants

pubmed: 33929322
doi: 10.7554/eLife.62915
pii: 62915
pmc: PMC8112868
doi:
pii:

Banques de données

Dryad
['10.5061/dryad.gf1vhhmpr', '10.5061/dryad.4b8gthtcf', '10.5061/dryad.3n5tb2rhd']

Types de publication

Evaluation Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Cancer Research UK
ID : A29283
Pays : United Kingdom
Organisme : Cancer Research UK
ID : C604/A25135
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N013700/1
Pays : United Kingdom
Organisme : Department of Health
Pays : United Kingdom

Informations de copyright

© 2021, Opzoomer et al.

Déclaration de conflit d'intérêts

JO, JT, KB, TM, NC, RB, SK, PN, BA, AR, MT, CH, FC, PP, MF, PB, JA No competing interests declared, SK Honoraria: Beckman Coulter, GWT-TUD, Alexion. Consulting or Advisory Role: Syneos Health. Research Funding: Celgene, Novartis pharmaceutical

Références

Bioinformatics. 2016 Apr 15;32(8):1241-3
pubmed: 26668002
Methods Mol Biol. 2019;1989:159-192
pubmed: 31077106
Cytometry B Clin Cytom. 2018 Sep;94(5):588-601
pubmed: 28865188
Cell Rep. 2019 Jul 16;28(3):819-831.e4
pubmed: 31315057
Haematologica. 2021 Apr 01;106(4):1047-1055
pubmed: 32241840
Cytometry A. 2016 Dec;89(12):1084-1096
pubmed: 27992111
F1000Res. 2017 May 26;6:748
pubmed: 28663787
Cell. 2015 Jul 2;162(1):184-97
pubmed: 26095251
Methods. 2015 Jul 1;82:55-63
pubmed: 25979346
Cytometry A. 2012 Sep;81(9):727-31
pubmed: 22887982
Oral Oncol. 2019 Jan;88:29-38
pubmed: 30616794
Cytometry. 2001 Nov 1;45(3):194-205
pubmed: 11746088
Methods Mol Biol. 2019;1989:93-108
pubmed: 31077101
Oncol Lett. 2017 Sep;14(3):3767-3773
pubmed: 28927145
Curr Top Microbiol Immunol. 2014;377:127-57
pubmed: 24590675
Int J Mol Sci. 2020 Mar 31;21(7):
pubmed: 32244396
Commun Biol. 2019 May 14;2:183
pubmed: 31098416
Cell Syst. 2018 Jan 24;6(1):25-36.e5
pubmed: 29289569
Neural Regen Res. 2020 Apr;15(4):663-664
pubmed: 31638088
Nat Biotechnol. 2018 Dec 03;:
pubmed: 30531897
Elife. 2020 Sep 07;9:
pubmed: 32894218
J Immunother Cancer. 2019 Oct 17;7(1):261
pubmed: 31623665
Nat Immunol. 2017 Jun 20;18(7):725-732
pubmed: 28632713
Cytometry A. 2015 Jul;87(7):636-45
pubmed: 25573116
Cytometry A. 2021 Apr 10;:
pubmed: 33840138
Blood. 2016 Sep 1;128(9):1193-205
pubmed: 27281795
Front Immunol. 2020 Mar 24;11:256
pubmed: 32265898
PLoS Comput Biol. 2014 Aug 28;10(8):e1003806
pubmed: 25167361
Nat Immunol. 2016 Jul 19;17(8):890-5
pubmed: 27434000
Nat Methods. 2017 Jul;14(7):707-709
pubmed: 28504682
PLoS Comput Biol. 2016 Sep 23;12(9):e1005112
pubmed: 27662185

Auteurs

James W Opzoomer (JW)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.

Jessica A Timms (JA)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.

Kevin Blighe (K)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.

Thanos P Mourikis (TP)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.

Nicolas Chapuis (N)

Institut Cochin, Institut National de la Santé et de la Recherche Médicale U1016, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8104, Université Paris Descartes, Paris, France.

Richard Bekoe (R)

UCL Cancer Institute, Paul O'Gorman Building, University College London, London, United Kingdom.

Sedigeh Kareemaghay (S)

Centre for Host Microbiome Interaction, FoDOCS, King's College, Guy's Hospital, London, United Kingdom.

Paola Nocerino (P)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.

Benedetta Apollonio (B)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.

Alan G Ramsay (AG)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.

Mahvash Tavassoli (M)

Centre for Host Microbiome Interaction, FoDOCS, King's College, Guy's Hospital, London, United Kingdom.

Claire Harrison (C)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.
Haematology Department, Guy's Hospital, London, United Kingdom.

Francesca Ciccarelli (F)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.
Cancer Systems Biology Laboratory, The Francis Crick Institute, London, United Kingdom.

Peter Parker (P)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.
Francis Crick Institute, London, United Kingdom.

Michaela Fontenay (M)

Institut Cochin, Institut National de la Santé et de la Recherche Médicale U1016, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8104, Université Paris Descartes, Paris, France.

Paul R Barber (PR)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.
UCL Cancer Institute, Paul O'Gorman Building, University College London, London, United Kingdom.

James N Arnold (JN)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.

Shahram Kordasti (S)

School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, United Kingdom.
Haematology Department, Guy's Hospital, London, United Kingdom.

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