Co-expression of NKp46 with activating or inhibitory receptors on, and cytokine production by, uterine endometrial NK cells in recurrent pregnancy loss.
Activating receptor
Cytokine
NKp46
Pregnancy
Uterine NK cell
Journal
Journal of reproductive immunology
ISSN: 1872-7603
Titre abrégé: J Reprod Immunol
Pays: Ireland
ID NLM: 8001906
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
23
12
2020
revised:
28
03
2021
accepted:
13
04
2021
pubmed:
1
5
2021
medline:
15
12
2021
entrez:
30
4
2021
Statut:
ppublish
Résumé
NKp46 (CD335) is one of the activating receptors expressed on NK cells and its expression is decreased in patients with reproductive failure. However, the reasons remain unknown. In this study, we aimed to clarify the significance of decreased NKp46 expression in reproductive failure. Uterine endometrial samples collected from 39 patients with recurrent pregnancy loss (RPL) were assigned to high- or low-risk groups based on an 18 % ratio of CD16
Identifiants
pubmed: 33930666
pii: S0165-0378(21)00054-1
doi: 10.1016/j.jri.2021.103324
pii:
doi:
Substances chimiques
Cytokines
0
NCR1 protein, human
0
Natural Cytotoxicity Triggering Receptor 1
0
Types de publication
Journal Article
Observational Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
103324Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.