Premature ejaculation and stress.
cortisol
premature ejaculation
stress
Journal
Andrologia
ISSN: 1439-0272
Titre abrégé: Andrologia
Pays: Germany
ID NLM: 0423506
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
revised:
15
04
2021
received:
22
02
2021
accepted:
18
04
2021
pubmed:
2
5
2021
medline:
9
7
2021
entrez:
1
5
2021
Statut:
ppublish
Résumé
Recent findings indicate that men with premature ejaculation report more frequent sexual problems associated with increased anxiety and interpersonal difficulties. Bearing this in mind, the neuroendocrine changes were examined in men with premature ejaculation and compared to other indicators of stressful experiences to see whether there can be any correlation which could indicate how these factors may contribute to the aetiology of premature ejaculation. Our study comprised 60 male outpatients diagnosed as having secondary premature ejaculation. Clinical examinations were focused on biochemical analysis of cortisol and psychometric scoring using a diagnostic tool for premature ejaculation, traumatic stress and somatoform dissociation. The control group consisted of a 60 healthy men. The results showed significant Spearman correlations of the Premature Ejaculation Diagnostic Tool score with Trauma Symptom Checklist score (R = .86), cortisol level (R = .47) and Somatoform Dissociation Questionnaire score (R = .61). In the control group, the results did not reach statistical significance. Spearman correlations of the Premature Ejaculation Diagnostic Tool score with Trauma symptoms checklist score was (R = .21), cortisol (R = .27) and with Somatoform dissociation questionnaire score (R = .25). These results represent the first reported findings documenting the relationship of traumatic stress indicators with the experience of secondary premature ejaculation and cortisol levels.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e14093Informations de copyright
© 2021 Wiley-VCH GmbH.
Références
Bogaert, A. F., & Brotto, L. A. (2014). Object of desire self-consciousness theory. Journal of Sex and Marital Therapy, 40(4), 323-338. https://doi.org/10.1080/0092623X.2012.756841
Briere, J. (2006). Dissociative symptoms and trauma exposure: Specificity, affect dysregulation, and posttraumatic stress. The Journal of Nervous and Mental Disease, 194(2), 78-82. https://doi.org/10.1097/01.nmd.0000198139.47371.54
Brotto, L., Atallah, S., Johnson-Agbakwu, C., Rosenbaum, T., Abdo, C., Byers, E. S., Graham, C., Nobre, P., & Wylie, K. (2016). Psychological and interpersonal dimensions of sexual function and dysfunction. The Journal of Sexual Medicine, 13(4), 538-571. https://doi.org/10.1016/j.jsxm.2016.01.019
Buvat, J. (2011). Pathophysiology of premature ejaculation. The Journal of Sexual Medicine, 8(Suppl 4), 316-327. https://doi.org/10.1111/j.1743-6109.2011.02384.x
Carani, C., Isidori, A. M., Granata, A., Carosa, E., Maggi, M., Lenzi, A., & Jannini, E. A. (2005). Multicenter study on the prevalence of sexual symptoms in male hypo-and hyperthyroid patients. The Journal of Clinical Endocrinology & Metabolism, 90(12), 6472-6479. https://doi.org/10.1210/jc.2005-1135
Chung, E., Gilbert, B., Perera, M., & Roberts, M. J. (2015). Premature ejaculation: A clinical review for the general physician. Australian Family Physician, 44(10), 737-743.
Ciocca, G., Limoncin, E., Mollaioli, D., Gravina, G. L., Di Sante, S., Carosa, E., Lenzi, A., & Jannini, E. A. (2013). Integrating psychotherapy and pharmacotherapy in the treatment of premature ejaculation. Arab Journal of Urology, 11(3), 305-312. https://doi.org/10.1016/j.aju.2013.04.011
Corona, G., Jannini, E. A., Lotti, F., Boddi, V., De Vita, G., Forti, G., Lenzi, A., Mannucci, E., & Maggi, M. (2011). Premature and delayed ejaculation: Two ends of a single continuum influenced by hormonal milieu. International Journal of Andrology, 34(1), 41-48. https://doi.org/10.1111/j.1365-2605.2010.01059.x
El-Nashaar, A., & Shamloul, R. (2007). Antibiotic treatment can delay ejaculation in patients with premature ejaculation and chronic bacterial prostatitis. The Journal of Sexual Medicine, 4(2), 491-496. https://doi.org/10.1111/j.1743-6109.2006.00243.x
Erdogan, A., Demirbas, M., Oner, S., Aydos, M. M., Sambel, M., & Yilmaz, C. (2019). Comparison of the levels of the serotonin metabolite, 5-hydroxyindole acetic acid, in cerebrospinal fluid from patients with and without premature ejaculation. Revista Internacional De Andrología, 17(2), 41-45. https://doi.org/10.1016/j.androl.2018.01.001
Fiala, L., & Lenz, J. (2020). Psychosocial stress, somatoform dissociative symptoms and free testosterone in premature ejaculation. Andrologia, 52(11), e13828. https://doi.org/10.1111/and.13828
Fiala, L., Lenz, J., & Sajdlova, R. (2021). Effect of increased prolactin and psychosocial stress on erectile function. Andrologia, 53(4), e14009. https://doi.org/10.1111/and.14009
Graziottin, A., & Althof, S. (2011). What does premature ejaculation mean to the man, the woman, and the couple? The Journal of Sexual Medicine, 8(Suppl 4), 304-309. https://doi.org/10.1111/j.1743-6109.2011.02426.x
Hanafy, S., Hamed, A. M., & Hilmy Samy, M. S. (2019). Prevalence of premature ejaculation and its impact on the quality of life: Results from a sample of Egyptian patients. Andrologia, 51(8), e13298. https://doi.org/10.1111/and.13298
Jannini, E. A., Simonelli, C., & Lenzi, A. (2002). Disorders of ejaculation. Journal of Endocrinological Investigation, 25(11), 1006-1019. https://doi.org/10.1007/BF03344077
Kalaitzidou, I., Venetikou, M. S., Konstadinidis, K., Artemiadis, A. K., Chrousos, G., & Darviri, C. (2014). Stress management and erectile dysfunction: A pilot comparative study. Andrologia, 46(6), 698-702. https://doi.org/10.1111/and.12129
Limoncin, E., Tomassetti, M., Gravina, G. L., Ciocca, G., Carosa, E., Di Sante, S., Gentile, V., Mirone, V., Montorsi, F., Lenzi, A., & Jannini, E. A. (2013). Premature ejaculation results in female sexual distress: Standardization and validation of a new diagnostic tool for sexual distress. Journal of Urology, 189(5), 1830-1835. https://doi.org/10.1016/j.juro.2012.11.007
Malviya, N., Malviya, S., Jain, S., & Vyas, S. (2016). A review of the potential of medicinal plants in the management and treatment of male sexual dysfunction. Andrologia, 48(8), 880-893. https://doi.org/10.1111/and.12677
Nijenhuis, E. R., Spinhoven, P., Van Dyck, R., Van der Hart, O., & Vanderlinden, J. (1996). The development and psychometric characteristics of the somatoform dissociation questionnaire (SDQ-20). The Journal of Nervous and Mental Disease, 184(11), 688-694. https://doi.org/10.1097/00005053-199611000-00006
Rosen, R. C., & Althof, S. (2008). Impact of premature ejaculation: The psychological, quality of life, and sexual relationship consequences. The Journal of Sexual Medicine, 5(6), 1296-1307. https://doi.org/10.1111/j.1743-6109.2008.00825.x
Rowland, D. L. (2011). Psychological impact of premature ejaculation and barriers to its recognition and treatment. Current Medical Research and Opinion, 27(8), 1509-1518. https://doi.org/10.1185/03007995.2011.590968
Shamloul, R., & el-Nashaar, A., (2006). Chronic prostatitis in premature ejaculation: A cohort study in 153 men. The Journal of Sexual Medicine, 3(1), 150-154. https://doi.org/10.1111/j.1743-6109.2005.00107.x
Symonds, T., Perelman, M. A., Althof, S., Giuliano, F., Martin, M., May, K., Abraham, L., Crossland, A., & Morris, M. (2007). Development and validation of a premature ejaculation diagnostic tool. European Urology, 52(2), 565-573. https://doi.org/10.1016/j.eururo.2007.01.028
Waldinger, M. D., Zwinderman, A. H., Olivier, B., & Schweitzer, D. H. (2008). Geometric mean IELT and premature ejaculation: Appropriate statistics to avoid overestimation of treatment efficacy. Journal of Sexual Medicine, 5(2), 492-499. https://doi.org/10.1111/j.1743-6109.2007.00696.x
Wang, B., Yang, C., & Tang, K. (2013). Serum leptin and 5-hydroxytryptamine measurements for the diagnosis and treatment of premature ejaculation. Urology, 82(6), 1336-1340. https://doi.org/10.1016/j.urology.2013.08.009