p16 loss facilitate hydroquinone-induced malignant transformation of TK6 cells through promoting cell proliferation and accelerating the cell cycle progression.
cell cycle
hydroquinone
malignant transformation
p16
Journal
Environmental toxicology
ISSN: 1522-7278
Titre abrégé: Environ Toxicol
Pays: United States
ID NLM: 100885357
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
received:
10
03
2021
accepted:
17
04
2021
pubmed:
2
5
2021
medline:
6
7
2021
entrez:
1
5
2021
Statut:
ppublish
Résumé
The p16
Substances chimiques
CDKN2A protein, human
0
Cyclin-Dependent Kinase Inhibitor p16
0
Hydroquinones
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1591-1599Subventions
Organisme : Dongguan Key Laboratory of Environmental Medicine
Organisme : Guangdong Medical University
ID : GDMU2018099
Organisme : Guangdong Provincial Natural Science Foundation
ID : 2018A030313580
Organisme : National Natural Science Foundation of China
ID : 81803278
Organisme : GuangdongProvincial major scientific research projects of ordinary universities
ID : 2017KZDXM041
Organisme : Provincial and municipal joint projects
ID : 4SG18056G
Organisme : Provincial and municipal joint projects
ID : 4SG18102G
Organisme : Provincial and municipal joint projects
ID : 4SG18004G
Organisme : Provincial and municipal joint projects
ID : 4SG17043
Informations de copyright
© 2021 Wiley Periodicals LLC.
Références
Lee JS, Yang EJ, Kim IS. Hydroquinone-induced apoptosis of human lymphocytes through caspase 9/3 pathway. Mol Biol Rep. 2012;39(6):6737-6743.
Huang J, Zhao M, Li X, et al. The cytotoxic effect of the benzene metabolite hydroquinone is mediated by the modulation of MDR1 expression via the NF-kappaB signaling pathway. Cell Physiol Biochem. 2015;37(2):592-602.
North M, Shuga J, Fromowitz M, et al. Modulation of Ras signaling alters the toxicity of hydroquinone, a benzene metabolite and component of cigarette smoke. BMC Cancer. 2014;14:6.
Bahadar H, Maqbool F, Mostafalou S, et al. The molecular mechanisms of liver and islets of Langerhans toxicity by benzene and its metabolite hydroquinone in vivo and in vitro. Toxicol Mech Methods. 2015;25(8):628-636.
Zhang F, Xie R, Munoz FM, Lau SS, Monks TJ. PARP-1 hyperactivation and reciprocal elevations in intracellular Ca2+ during ROS-induced nonapoptotic cell death. Toxicol Sci. 2014;140(1):118-134.
Khalade A, Jaakkola MS, Pukkala E, Jaakkola JJ. Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis. Environ Health. 2010;9:31.
McDonald TA, Holland NT, Skibola C, Duramad P, Smith MT. Hypothesis: phenol and hydroquinone derived mainly from diet and gastrointestinal flora activity are causal factors in leukemia. Leukemia. 2001;15(1):10-20.
Galvan N, Lim S, Zmugg S, Smith MT, Zhang L. Depletion of WRN enhances DNA damage in HeLa cells exposed to the benzene metabolite, hydroquinone. Mutat Res. 2008;649(1-2):54-61.
Chen Y, Chen J, Yun L, et al. Hydroquinone-induced malignant transformation of TK6 cells by facilitating SIRT1-mediated p53 degradation and up-regulating KRAS. Toxicol Lett. 2016;259:133-142.
Sherr CJ. Cancer cell cycles. Science. 1996;274(5293):1672-1677.
Morsczeck C, Hullmann M, Reck A, Reichert TE. The cell cycle regulator protein P16 and the cellular senescence of dental follicle cells. Mol Cell Biochem. 2018;439(1-2):45-52.
Lu Y, Ma W, Li Z, Lu J, Wang X. The interplay between p16 serine phosphorylation and arginine methylation determines its function in modulating cellular apoptosis and senescence. Sci Rep. 2017;7:41390.
Tong R, Yang Q, Wang C, Bi F, Jiang B. OVCA1 expression and its correlation with the expression levels of cyclin D1 and p16 in cervical cancer and intraepithelial neoplasia. Oncol Lett. 2017;13(5):2929-2936.
Zainuddin A, Chua KH, Tan JK, Jaafar F, Makpol S. Gamma-Tocotrienol prevents cell cycle arrest in aged human fibroblast cells through p16(INK4a) pathway. J Physiol Biochem. 2017;73(1):59-65.
Ruas M, Peters G. The p16INK4a/CDKN2A tumor suppressor and its relatives. Biochim Biophys Acta. 1998;1378(2):F115-F177.
Li Y, Nichols MA, Shay JW, Xiong Y. Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb. Cancer Res. 1994;54(23):6078-6082.
Hara E, Smith R, Parry D, Tahara H, Stone S, Peters G. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol Cell Biol. 1996;16(3):859-867.
Feng W, Han Z, Zhu R, Liu P, Liu S. Association of p16 gene methylation with prostate cancer risk: a meta-analysis. J BUON. 2015;20(4):1074-1080.
Du W, Liu Z, Zhu W, et al. CSN6 promotes tumorigenesis of gastric cancer by ubiquitin-independent proteasomal degradation of p16(INK4a). Cancer Biol Med. 2019;16(3):514-529.
Yang Z, Hu J, Li D, Pan X. Adenovirus with p16 gene exerts antitumor effect on laryngeal carcinoma Hep2 cells. Mol Med Rep. 2016;14(2):1425-1429.
Stone S, Jiang P, Dayananth P, et al. Complex structure and regulation of the P16 (MTS1) locus. Cancer Res. 1995;55(14):2988-2994.
Carlos de Vicente J, Junquera Gutierrez LM, Zapatero AH, Fresno Forcelledo MF, Hernandez-Vallejo G, Lopez Arranz JS. Prognostic significance of p53 expression in oral squamous cell carcinoma without neck node metastases. Head Neck. 2004;26(1):22-30.
Legan M. Cyclooxygenase-2, p53 and glucose transporter-1 as predictors of malignancy in the development of gallbladder carcinomas. Bosn J Basic Med Sci. 2010;10(3):192-196.
Stefanaki C, Stefanaki K, Antoniou C, et al. G1 cell cycle regulators in congenital melanocytic nevi. Comparison with acquired nevi and melanomas. J Cutan Pathol. 2008;35(9):799-808.
Rufini A, Tucci P, Celardo I, Melino G. Senescence and aging: the critical roles of p53. Oncogene. 2013;32(43):5129-5143.
Rayess H, Wang MB, Srivatsan ES. Cellular senescence and tumor suppressor gene p16. Int J Cancer. 2012;130(8):1715-1725.
Escobar PA, Smith MT, Vasishta A, Hubbard AE, Zhang L. Leukaemia-specific chromosome damage detected by comet with fluorescence in situ hybridization (comet-FISH). Mutagenesis. 2007;22(5):321-327.
Ji Z, Zhang L, Guo W, McHale CM, Smith MT. The benzene metabolite, hydroquinone and etoposide both induce endoreduplication in human lymphoblastoid TK6 cells. Mutagenesis. 2009;24(4):367-372.
Platel A, Nesslany F, Gervais V, Claude N, Marzin D. Study of oxidative DNA damage in TK6 human lymphoblastoid cells by use of the thymidine kinase gene-mutation assay and the in vitro modified comet assay: determination of no-observed-genotoxic-effect-levels. Mutat Res. 2011;726(2):151-159.
Aguilera-Montilla N, Bailon E, Uceda-Castro R, et al. MMP-9 affects gene expression in chronic lymphocytic leukemia revealing CD99 as an MMP-9 target and a novel partner in malignant cell migration/arrest. Oncogene. 2019;38(23):4605-4619.
Ugarte-Berzal E, Bailon E, Amigo-Jimenez I, et al. A 17-residue sequence from the matrix metalloproteinase-9 (MMP-9) hemopexin domain binds alpha4beta1 integrin and inhibits MMP-9-induced functions in chronic lymphocytic leukemia B cells. J Biol Chem. 2012;287(33):27601-27613.
Fernandez PL, Hernandez L, Farre X, Campo E, Cardesa A. Alterations of cell cycle-regulatory genes in prostate cancer. Pathobiology. 2002;70(1):1-10.
Dai X, Chen C, Yang Q, et al. Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and promoting cell proliferation. Cell Death Dis. 2018;9(5):454.
Lummus SC, Donson AM, Gowan K, et al. p16 loss and E2F/cell cycle deregulation in infant posterior fossa ependymoma. Pediatr Blood Cancer. 2017;64(12):e26656.
Buj R, Aird KM. p16: cycling off the beaten path. Mol Cell Oncol. 2019;6(6):e1677140.
Buj R, Chen CW, Dahl ES, et al. Suppression of p16 induces mTORC1-mediated nucleotide metabolic reprogramming. Cell Rep. 2019;28(8):1971-1980.e8.
Haferkamp S, Becker TM, Scurr LL, Kefford RF, Rizos H. p16INK4a-induced senescence is disabled by melanoma-associated mutations. Aging Cell. 2008;7(5):733-745.
Hansen R, Oren M. p53; from inductive signal to cellular effect. Curr Opin Genet Dev. 1997;7(1):46-51.
Ko LJ, Prives C. p53: puzzle and paradigm. Genes Dev. 1996;10(9):1054-1072.