Prevalence and incidence of postpartum depression and environmental factors: The IGEDEPP cohort.

Cohort Studies Depression, Postpartum / epidemiology Female Humans Incidence Male Postpartum Period Pregnancy Prevalence Prospective Studies Risk Factors
Depression Incidence Life events Postpartum Prevalence

Journal

Journal of psychiatric research
ISSN: 1879-1379
Titre abrégé: J Psychiatr Res
Pays: England
ID NLM: 0376331

Informations de publication

Date de publication:
06 2021
Historique:
received: 21 09 2020
revised: 25 03 2021
accepted: 01 04 2021
pubmed: 2 5 2021
medline: 6 7 2021
entrez: 1 5 2021
Statut: ppublish

Résumé

IGEDEPP (Interaction of Gene and Environment of Depression during PostPartum) is a prospective multicenter cohort study of 3310 Caucasian women who gave birth between 2011 and 2016, with follow-up until one year postpartum. The aim of the current study is to describe the cohort and estimate the prevalence and cumulative incidence of early and late-onset postpartum depression (PPD). Socio-demographic data, personal and family psychiatric history, as well as stressful life events during childhood and pregnancy were evaluated at baseline. Early and late-onset PPD were assessed at 8 weeks and 1 year postpartum respectively, using DSM-5 criteria. The prevalence of early-onset PPD was 8.3% (95%CI 7.3-9.3), and late PPD 12.9% (95%CI 11.5-14.2), resulting in an 8-week cumulative incidence of 8.5% (95%CI 7.4-9.6) and a one-year cumulative incidence of PPD of 18.1% (95%CI: 17.1-19.2). Nearly half of the cohort (N = 1571, 47.5%) had a history of at least one psychiatric or addictive disorder, primarily depressive disorder (35%). Almost 300 women in the cohort (9.0%) reported childhood trauma. During pregnancy, 47.7% women experienced a stressful event, 30.2% in the first 8 weeks and 43.9% between 8 weeks and one year postpartum. Nearly one in five women reported at least one stressful postpartum event at 8 weeks. Incident depressive episodes affected nearly one in five women during the first year postpartum. Most women had stressful perinatal events. Further IGEDEPP studies will aim to disentangle the impact of childhood and pregnancy-related stressful events on postpartum mental disorders.

Sections du résumé

BACKGROUND
IGEDEPP (Interaction of Gene and Environment of Depression during PostPartum) is a prospective multicenter cohort study of 3310 Caucasian women who gave birth between 2011 and 2016, with follow-up until one year postpartum. The aim of the current study is to describe the cohort and estimate the prevalence and cumulative incidence of early and late-onset postpartum depression (PPD).
METHODS
Socio-demographic data, personal and family psychiatric history, as well as stressful life events during childhood and pregnancy were evaluated at baseline. Early and late-onset PPD were assessed at 8 weeks and 1 year postpartum respectively, using DSM-5 criteria.
RESULTS
The prevalence of early-onset PPD was 8.3% (95%CI 7.3-9.3), and late PPD 12.9% (95%CI 11.5-14.2), resulting in an 8-week cumulative incidence of 8.5% (95%CI 7.4-9.6) and a one-year cumulative incidence of PPD of 18.1% (95%CI: 17.1-19.2). Nearly half of the cohort (N = 1571, 47.5%) had a history of at least one psychiatric or addictive disorder, primarily depressive disorder (35%). Almost 300 women in the cohort (9.0%) reported childhood trauma. During pregnancy, 47.7% women experienced a stressful event, 30.2% in the first 8 weeks and 43.9% between 8 weeks and one year postpartum. Nearly one in five women reported at least one stressful postpartum event at 8 weeks.
CONCLUSION
Incident depressive episodes affected nearly one in five women during the first year postpartum. Most women had stressful perinatal events. Further IGEDEPP studies will aim to disentangle the impact of childhood and pregnancy-related stressful events on postpartum mental disorders.

Identifiants

DOI: 10.1016/j.jpsychires.2021.04.004 PMID: 33932643
pubmed: 33932643
pii: S0022-3956(21)00223-5
doi: 10.1016/j.jpsychires.2021.04.004
pii:
doi:

Types de publication

Journal Article Multicenter Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

366-374

Investigateurs

Emmanuelle Bertin (E)
Cecile Bourneuf (C)
Jeanne Colombe (J)
Laura Couppa (L)
Marc Dommergue (M)
Caroline Dubertret (C)
Fanny Georges (F)
Celine Hebbache (C)
Gilles Kayem (G)
Marie Le Bars (M)
Yann Le Strat (Y)
Jacques Lepercq (J)
Dominique Luton (D)
Julie Guiot Madhavi (JG)
Laurent Mandelbrot (L)
Jimmy Mullaert (J)
Cindy Parent (C)
Alix de Premorel (A)
Nicolas Ramoz (N)
Sarah Tebeka (S)
Yves Ville (Y)

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Sarah Tebeka (S)

Université de Paris, INSERM UMR1266, Institute of Psychiatry and Neurosciences, Team 1, Paris, France; Department of Psychiatry, AP-HP, Louis Mourier Hospital, F-92700, Colombes, France. Electronic address: sarah.tebeka@aphp.fr.

Yann Le Strat (Y)

Université de Paris, INSERM UMR1266, Institute of Psychiatry and Neurosciences, Team 1, Paris, France; Department of Psychiatry, AP-HP, Louis Mourier Hospital, F-92700, Colombes, France.

Alix De Premorel Higgons (A)

Université de Paris, INSERM UMR1266, Institute of Psychiatry and Neurosciences, Team 1, Paris, France; Department of Psychiatry, AP-HP, Louis Mourier Hospital, F-92700, Colombes, France.

Alexandra Benachi (A)

Université Paris Sud, Clamart, France; Department of Obstetrics and Gynecology, AP-HP, Antoine Beclere Hospital, Clamart, France.

Marc Dommergues (M)

Sorbonne University, Paris, France; Department of Obstetrics and Gynecology, AP-HP, Hôpital Universitaire Pitié-Salpêtrière, Paris, France.

Gilles Kayem (G)

Sorbonne University, Paris, France; Department of Obstetrics and Gynecology, AP-HP, Trousseau Hospital, Paris, France.

Jacques Lepercq (J)

Université de Paris, Departement Hospitalier Universitaire Risks in Pregnancy, Paris, France; Port-Royal Maternity Unit, Cochin Hospital, AP-HP, Paris, France.

Dominique Luton (D)

Université de Paris, Departement Hospitalier Universitaire Risks in Pregnancy, Paris, France; Department of Obstetrics and Gynecology, AP-HP, Bichat Hospital, Paris, France.

Laurent Mandelbrot (L)

Université de Paris, Departement Hospitalier Universitaire Risks in Pregnancy, Paris, France; Department of Obstetrics and Gynecology, AP-HP, Louis Mourier Hospital, Colombes, France.

Yves Ville (Y)

Sorbonne University, Paris, France; Department of Obstetrics and Gynecology, AP-HP, Necker Enfant Malade Hospital, Paris, France.

Nicolas Ramoz (N)

Université de Paris, INSERM UMR1266, Institute of Psychiatry and Neurosciences, Team 1, Paris, France.

Sophie Tezenas du Montcel (S)

Sorbonne University, Paris, France; INSERM, Institut Pierre Louis D'Epidémiologie et de Santé Publique IPLESP, AP-HP, Hôpitaux Universitaires Pitié Salpêtrière - Charles Foix, F75013, Paris, France.

Jimmy Mullaert (J)

Department of Epidemiology, Biostatistics and Clinical Research, AP-HP, Hôpital Bichat, F-75018, Paris, France; Université de Paris, IAME, INSERM, F-75018 Paris, France.

Caroline Dubertret (C)

Université de Paris, INSERM UMR1266, Institute of Psychiatry and Neurosciences, Team 1, Paris, France; Department of Psychiatry, AP-HP, Louis Mourier Hospital, F-92700, Colombes, France.

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Classifications MeSH

questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Prevalence and incidence of postpartum...
questionsmedicales.fr › Troubles mentaux › Troubles de l'humeur › Trouble dépressif › Dépression du postpartum › Prevalence and incidence of postpartum...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Prevalence and incidence of postpartum...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Incidence › Prevalence and incidence of postpartum...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Période du postpartum › Prevalence and incidence of postpartum...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Prevalence and incidence of postpartum...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Prévalence › Prevalence and incidence of postpartum...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Prevalence and incidence of postpartum...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Prevalence and incidence of postpartum...