Virucidal and antiviral effects of Thymus vulgaris essential oil on feline coronavirus.
FIP
Feline Coronavirus
Thymus Essential Oil
Thymus vulgaris
Journal
Research in veterinary science
ISSN: 1532-2661
Titre abrégé: Res Vet Sci
Pays: England
ID NLM: 0401300
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
09
12
2020
revised:
12
04
2021
accepted:
19
04
2021
pubmed:
2
5
2021
medline:
24
6
2021
entrez:
1
5
2021
Statut:
ppublish
Résumé
Feline infectious peritonitis (FIP) is a fatal systemic disease of felids caused by a Coronavirus (CoV) (FIPV). In spite of its clinical relevance and impact on feline health, currently the therapeutic possibilities for treatment of FIP in cats are limited. The emergence of the pandemic Severe Respiratory Syndrome (SARS) coronavirus (CoV) type 2 (SARS-CoV-2), etiological agent of the 2019 Coronavirus Disease (COVID-19), able to infect a broad spectrum of animal species including cats, triggered the interest for the development of novel molecules with antiviral activity for treatment of CoV infections in humans and animals. Essential oils (EOs) have raised significant attention for their antiviral properties integrating and, in some cases, replacing conventional drugs. Thymus vulgaris EO (TEO) has been previously shown to be effective against several RNA viruses including CoVs. In the present study the antiviral efficacy of TEO against FIPV was evaluated in vitro. TEO at 27 μg/ml was able to inhibit virus replication with a significant reduction of 2 log10 TCID
Identifiants
pubmed: 33932822
pii: S0034-5288(21)00123-5
doi: 10.1016/j.rvsc.2021.04.024
pmc: PMC8061179
pii:
doi:
Substances chimiques
Oils, Volatile
0
Plant Oils
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
44-47Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.
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