The predictive value of creatinine clearance for mortality in patients undergoing revascularization.


Journal

Journal of cardiothoracic surgery
ISSN: 1749-8090
Titre abrégé: J Cardiothorac Surg
Pays: England
ID NLM: 101265113

Informations de publication

Date de publication:
01 May 2021
Historique:
received: 14 10 2020
accepted: 19 04 2021
entrez: 2 5 2021
pubmed: 3 5 2021
medline: 2 7 2021
Statut: epublish

Résumé

Renal function plays a significant role in the prognosis and management of patients with multi-vessel coronary artery disease (CAD) referred for revascularization. Current data lack precise risk stratification using estimated glomerular filtration rate (eGFR) and creatinine clearance. This prospective study includes a three-year follow-up of 1112 consecutive patients with multi-vessel CAD enrolled in the 22 hospitals in Israel that perform coronary angiography. The Mayo formula yielded the highest mean eGFR (90 ± 26 mL/min per 1.73m Our data suggest that while the Mayo formula is not currently recommended by any nephrology guidelines, it may be an alternative formula to predict mortality among patients with multivessel CAD, including to the widely used MDRD formula.

Sections du résumé

BACKGROUND BACKGROUND
Renal function plays a significant role in the prognosis and management of patients with multi-vessel coronary artery disease (CAD) referred for revascularization. Current data lack precise risk stratification using estimated glomerular filtration rate (eGFR) and creatinine clearance.
METHODS METHODS
This prospective study includes a three-year follow-up of 1112 consecutive patients with multi-vessel CAD enrolled in the 22 hospitals in Israel that perform coronary angiography.
RESULTS RESULTS
The Mayo formula yielded the highest mean eGFR (90 ± 26 mL/min per 1.73m
CONCLUSIONS CONCLUSIONS
Our data suggest that while the Mayo formula is not currently recommended by any nephrology guidelines, it may be an alternative formula to predict mortality among patients with multivessel CAD, including to the widely used MDRD formula.

Identifiants

pubmed: 33933109
doi: 10.1186/s13019-021-01502-1
pii: 10.1186/s13019-021-01502-1
pmc: PMC8088555
doi:

Substances chimiques

Creatinine AYI8EX34EU

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

120

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Auteurs

Eilon Ram (E)

Department of Cardiac Surgery, Leviev Cardiothoracic and Vascular Center, 52621, Tel Hashomer, Israel. eilon.ram@sheba.health.gov.il.
Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. eilon.ram@sheba.health.gov.il.

Pazit Beckerman (P)

Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Nephrology, Leviev Cardiothoracic and Vascular Center, 52621, Tel Hashomer, Israel.

Amit Segev (A)

Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Cardiology, Leviev Cardiothoracic and Vascular Center, 52621, Tel Hashomer, Israel.

Nir Shlomo (N)

Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Cardiology, Leviev Cardiothoracic and Vascular Center, 52621, Tel Hashomer, Israel.

Abigail Atlas-Lazar (A)

Maccabi Health Services, Tel Aviv, Israel.

Leonid Sternik (L)

Department of Cardiac Surgery, Leviev Cardiothoracic and Vascular Center, 52621, Tel Hashomer, Israel.
Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Ehud Raanani (E)

Department of Cardiac Surgery, Leviev Cardiothoracic and Vascular Center, 52621, Tel Hashomer, Israel.
Sheba Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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