Richter's transformation as leptomeningeal infiltration in a chronic lymphocytic leukemia patient receiving venetoclax. Could blood-brain barrier be a disease "sanctuary" during venetoclax treatment?
Richter's transformation
blood‐brain barrier
chronic lymphocytic leukemia
leptomeningeal infiltration
venetoclax
Journal
Clinical case reports
ISSN: 2050-0904
Titre abrégé: Clin Case Rep
Pays: England
ID NLM: 101620385
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
09
01
2021
accepted:
16
02
2021
entrez:
3
5
2021
pubmed:
4
5
2021
medline:
4
5
2021
Statut:
epublish
Résumé
Our unique case of Richter's Transformation presenting as leptomeningial infiltration in a CLL patient receiving venetoclax raises questions on whether the drug penetrates the blood-brain barrier and at what extend, especially in reduced doses given for drug-drug interactions.
Identifiants
pubmed: 33936674
doi: 10.1002/ccr3.4002
pii: CCR34002
pmc: PMC8077271
doi:
Types de publication
Case Reports
Langues
eng
Pagination
2249-2253Informations de copyright
© 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
Déclaration de conflit d'intérêts
None declared.
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