Feasibility of low-dose contrast media in run-off CT angiography on dual-layer spectral detector CT.
Spectral detector computed tomography
contrast media (CM)
lower extremity
virtual monoenergetic images (VMIs)
Journal
Quantitative imaging in medicine and surgery
ISSN: 2223-4292
Titre abrégé: Quant Imaging Med Surg
Pays: China
ID NLM: 101577942
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
entrez:
3
5
2021
pubmed:
4
5
2021
medline:
4
5
2021
Statut:
ppublish
Résumé
The aim of the present study was to assess the feasibility of applying low-dose contrast media (CM), and to explore the optimal virtual monoenergetic images (VMIs) in run-off computed tomography (CT) angiography (CTA) on dual-layer spectral detector CT (SDCT). Forty patients were randomly assigned into a control group using routine volume CM (group A) and an experimental group using half-volume CM (group B). In groups A and B, 120 kVp polychromatic conventional images were generated via hybrid iterative reconstruction algorithm defined as A1 and B1, respectively. Additionally, in group B, VMIs (range, 40-120 keV) were reconstructed via a spectral reconstruction algorithm defined as B2-B10. Vascular attenuation, noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and radiation dose were evaluated. Subjective evaluation was performed using a 5-point scale. The patient demographics and radiation dose demonstrated no significant difference between groups A and B [dose length product (DLP): 1,823.45±512.68 It is feasible to perform run-off CTA using low-dose CM with VMI on SDCT. The VMIs at 40-50 keV were the optimal choice and did not compromise IQ.
Sections du résumé
BACKGROUND
BACKGROUND
The aim of the present study was to assess the feasibility of applying low-dose contrast media (CM), and to explore the optimal virtual monoenergetic images (VMIs) in run-off computed tomography (CT) angiography (CTA) on dual-layer spectral detector CT (SDCT).
METHODS
METHODS
Forty patients were randomly assigned into a control group using routine volume CM (group A) and an experimental group using half-volume CM (group B). In groups A and B, 120 kVp polychromatic conventional images were generated via hybrid iterative reconstruction algorithm defined as A1 and B1, respectively. Additionally, in group B, VMIs (range, 40-120 keV) were reconstructed via a spectral reconstruction algorithm defined as B2-B10. Vascular attenuation, noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and radiation dose were evaluated. Subjective evaluation was performed using a 5-point scale.
RESULTS
RESULTS
The patient demographics and radiation dose demonstrated no significant difference between groups A and B [dose length product (DLP): 1,823.45±512.68
CONCLUSIONS
CONCLUSIONS
It is feasible to perform run-off CTA using low-dose CM with VMI on SDCT. The VMIs at 40-50 keV were the optimal choice and did not compromise IQ.
Identifiants
pubmed: 33936965
doi: 10.21037/qims-20-925
pii: qims-11-05-1796
pmc: PMC8047342
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1796-1804Informations de copyright
2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/qims-20-925). The authors have no conflicts of interest to declare.
Références
Br J Radiol. 2019 Feb;92(1094):20180215
pubmed: 30407841
Eur J Radiol. 2018 Jan;98:118-125
pubmed: 29279149
Circ Cardiovasc Interv. 2010 Aug;3(4):346-50
pubmed: 20587788
AJR Am J Roentgenol. 2019 Feb;212(2):467-474
pubmed: 30476460
Quant Imaging Med Surg. 2020 Mar;10(3):592-603
pubmed: 32269920
Chem Rev. 2013 Mar 13;113(3):1641-66
pubmed: 23210836
Insights Imaging. 2017 Dec;8(6):589-598
pubmed: 28986761
Eur Radiol. 2018 Jul;28(7):2745-2755
pubmed: 29404773
Int J Cardiovasc Imaging. 2018 Aug;34(8):1265-1275
pubmed: 29516228
Eur Radiol. 2016 Dec;26(12):4380-4389
pubmed: 26960541
N Engl J Med. 2006 Jan 26;354(4):379-86
pubmed: 16436769
AJR Am J Roentgenol. 2008 Jul;191(1):43-9
pubmed: 18562723
Korean J Radiol. 2017 Jul-Aug;18(4):555-569
pubmed: 28670151
Int J Cardiovasc Imaging. 2014 Dec;30(8):1613-20
pubmed: 25053514
Abdom Radiol (NY). 2017 Mar;42(3):702-709
pubmed: 28084546
PLoS One. 2014 Jun 10;9(6):e99112
pubmed: 24915439
Diagn Interv Imaging. 2018 Sep;99(9):561-568
pubmed: 29753661
Invest Radiol. 2016 Feb;51(2):139-46
pubmed: 26561048
J Am Podiatr Med Assoc. 2010 Sep-Oct;100(5):412-23
pubmed: 20847356
Radiology. 2014 Oct;273(1):153-9
pubmed: 24937693
PLoS One. 2015 Sep 29;10(9):e0139275
pubmed: 26418007
Eur Radiol. 1999;9(8):1602-13
pubmed: 10525875
J Cardiovasc Comput Tomogr. 2017 Jan - Feb;11(1):33-39
pubmed: 28096049
Radiology. 2003 Aug;228(2):303-8
pubmed: 12819342
Heart Views. 2013 Jul;14(3):106-16
pubmed: 24696755