Pelvic organ prolapse recurrence after apical prolapse repair: does obesity matter?
Apical prolapse repair
Body mass index
Obesity
Pelvic organ prolapse recurrence
Journal
International urogynecology journal
ISSN: 1433-3023
Titre abrégé: Int Urogynecol J
Pays: England
ID NLM: 101567041
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
28
12
2020
accepted:
13
04
2021
pubmed:
4
5
2021
medline:
1
4
2022
entrez:
3
5
2021
Statut:
ppublish
Résumé
We hypothesized obesity increases the risk of pelvic organ prolapse recurrence (POP-R) after primary apical prolapse repair. We conducted a retrospective cohort study of 353 women who underwent primary apical prolapse surgery from 2011 to 2016. Demographic and clinical data were abstracted from medical records. Multivariable Cox proportional hazard models were used to generate hazard ratios (HR) for association between obesity (BMI ≥ 30 kg/m Ten percent of women developed POP-R. The median follow-up time was 7 months (range 1.4, 63.9). Twenty-four percent of patients were Black and 70% were White; 37% were obese. After controlling for confounders, obese women did not have an increased risk of POP-R (aHR 1.39; 95% CI 0.67, 2.86, p = 0.38). Although only marginally statistically significant, patients who developed POP-R were more likely to be current smokers (aHR 3.48, 95% CI 1.14, 10.67; p = 0.06) or previous smokers (aHR 1.86, 95% CI 0.82, 4.24, p = 0.06) in comparison to non-smokers. Sensitivity analysis showed loss to follow-up had the potential to influence our results. Obesity was not a risk factor for POP-R in our cohort. Larger, prospective studies with longer postoperative follow-up time are needed to fully elucidate the relationship between obesity and POP-R.
Identifiants
pubmed: 33938961
doi: 10.1007/s00192-021-04806-x
pii: 10.1007/s00192-021-04806-x
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
275-284Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2021. The International Urogynecological Association.
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