Fluorine-18 labelled Ruppert-Prakash reagent ([
Journal
Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838
Informations de publication
Date de publication:
27 May 2021
27 May 2021
Historique:
pubmed:
5
5
2021
medline:
5
5
2021
entrez:
4
5
2021
Statut:
ppublish
Résumé
This article describes the first synthesis and application of fluorine-18 labelled Ruppert-Prakash reagent [18F]Me3SiCF3. [18F]Me3SiCF3 was synthesized from [18F]fluoroform with radiochemical yields of 85-95% and radiochemical purities of >95% within 20 minutes. 18F-trifluoromethylated compounds were successfully prepared by reaction of [18F]Me3SiCF3 with benzaldehydes, acetophenones and benzophenones.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM