The use of transgenics in the laboratory axolotl.
Ambystoma mexicanum
genome editing
laboratory axolotl
transgenics
Journal
Developmental dynamics : an official publication of the American Association of Anatomists
ISSN: 1097-0177
Titre abrégé: Dev Dyn
Pays: United States
ID NLM: 9201927
Informations de publication
Date de publication:
06 2022
06 2022
Historique:
revised:
10
03
2021
received:
29
12
2020
accepted:
29
04
2021
pubmed:
6
5
2021
medline:
7
6
2022
entrez:
5
5
2021
Statut:
ppublish
Résumé
The ability to generate transgenic animals sparked a wave of research committed to implementing such technology in a wide variety of model organisms. Building a solid base of ubiquitous and tissue-specific reporter lines has set the stage for later interrogations of individual cells or genetic elements. Compared to other widely used model organisms such as mice, zebrafish and fruit flies, there are only a few transgenic lines available in the laboratory axolotl (Ambystoma mexicanum), although their number is steadily expanding. In this review, we discuss a brief history of the transgenic methodologies in axolotl and their advantages and disadvantages. Next, we discuss available transgenic lines and insights we have been able to glean from them. Finally, we list challenges when developing transgenic axolotl, and where further work is needed in order to improve their standing as both a developmental and regenerative model.
Identifiants
pubmed: 33949035
doi: 10.1002/dvdy.357
pmc: PMC8568732
mid: NIHMS1702444
doi:
Types de publication
Journal Article
Review
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
942-956Subventions
Organisme : NIGMS NIH HHS
ID : P20 GM103423
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM104318
Pays : United States
Informations de copyright
© 2021 The Authors. Developmental Dynamics published by Wiley Periodicals LLC on behalf of American Association for Anatomy.
Références
Genome Res. 2019 Feb;29(2):317-324
pubmed: 30679309
J Vis Exp. 2011 Jun 03;(52):
pubmed: 21673643
Nat Rev Genet. 2005 Mar;6(3):167-78
pubmed: 15738961
Nat Commun. 2022 Mar 3;13(1):1141
pubmed: 35241664
Development. 2011 Jan;138(1):169-77
pubmed: 21138979
Dev Growth Differ. 2015 Jan;57(1):24-39
pubmed: 25431100
Nature. 2009 Jul 2;460(7251):60-5
pubmed: 19571878
Dev Cell. 2003 Apr;4(4):509-19
pubmed: 12689590
Dev Biol. 2016 Aug 1;416(1):26-33
pubmed: 27316294
Nucleic Acids Res. 1999 Nov 15;27(22):4324-7
pubmed: 10536138
BMC Genomics. 2009 Jan 13;10:19
pubmed: 19144141
Mech Dev. 2002 Oct;118(1-2):91-8
pubmed: 12351173
Annu Rev Genet. 2011;45:247-71
pubmed: 21910633
Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13662-7
pubmed: 22869739
Development. 1996 Oct;122(10):3173-83
pubmed: 8898230
Sci Rep. 2018 Jan 12;8(1):593
pubmed: 29330493
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1250-4
pubmed: 4364530
Cell Stem Cell. 2014 Feb 6;14(2):174-87
pubmed: 24268695
Genetics. 2008 Sep;180(1):103-19
pubmed: 18723890
Sci Rep. 2017 Dec;7(1):6
pubmed: 28127056
Cell Res. 2015 May;25(5):634-7
pubmed: 25849248
Nat Protoc. 2018 Dec;13(12):2908-2943
pubmed: 30429597
Cold Spring Harb Protoc. 2009 Aug;2009(8):pdb.emo128
pubmed: 20147230
Nat Plants. 2016 Sep 12;2:16139
pubmed: 27618611
Genesis. 2005 Feb;41(2):87-98
pubmed: 15712266
Stem Cell Reports. 2013 Jun 04;1(1):90-103
pubmed: 24052945
Dev Biol. 2012 Aug 1;368(1):63-75
pubmed: 22627291
Dev Dyn. 2010 Dec;239(12):3275-84
pubmed: 20981826
Gene Ther. 2006 Oct;13(19):1382-90
pubmed: 16724096
Nat Cell Biol. 2021 Feb;23(2):198-208
pubmed: 33526902
Methods Mol Biol. 2014;1092:421-36
pubmed: 24318834
Development. 2016 Oct 1;143(19):3491-3505
pubmed: 27578793
Nat Commun. 2020 May 1;11(1):2141
pubmed: 32358538
Annu Rev Genet. 2006;40:363-83
pubmed: 16895466
PLoS One. 2009;4(2):e4640
pubmed: 19247481
NPJ Regen Med. 2016 Jun 09;1:16002
pubmed: 29302334
Development. 2014 May;141(10):2165-71
pubmed: 24764077
Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11153-7
pubmed: 7526391
Trends Biotechnol. 2013 Jul;31(7):397-405
pubmed: 23664777
Science. 2018 Oct 26;362(6413):
pubmed: 30262634
Dev Cell. 2016 Nov 21;39(4):411-423
pubmed: 27840105
Dev Dyn. 2005 Jun;233(2):562-9
pubmed: 15778984
Methods Mol Biol. 2016;1338:119-26
pubmed: 26443218
Stem Cell Reports. 2014 Sep 9;3(3):444-59
pubmed: 25241743
Dev Biol. 2006 Feb 15;290(2):386-97
pubmed: 16387293
Mol Cell Biol. 2004 Sep;24(17):7636-42
pubmed: 15314171
Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12501-12506
pubmed: 29087939
PLoS One. 2010 May 12;5(5):e10611
pubmed: 20485554
Methods Cell Biol. 2011;104:173-94
pubmed: 21924163
Nature. 2018 Feb 1;554(7690):50-55
pubmed: 29364872
Regeneration (Oxf). 2015 Apr 08;2(1):37-43
pubmed: 27499866
Nature. 2019 Apr;568(7751):193-197
pubmed: 30944477
Dev Biol. 1995 Sep;171(1):123-9
pubmed: 7556889
Nat Protoc. 2011 May;6(5):600-8
pubmed: 21527918
Curr Genomics. 2010 Apr;11(2):115-28
pubmed: 20885819
Int J Dev Biol. 2019;63(6-7):281-286
pubmed: 31250911
Trends Cell Biol. 2016 Jan;26(1):52-64
pubmed: 26437586
Methods Mol Biol. 2015;1290:297-305
pubmed: 25740495
Nat Rev Genet. 2009 Dec;10(12):845-58
pubmed: 19920852
Nat Biotechnol. 2001 Aug;19(8):746-50
pubmed: 11479567
BMC Biotechnol. 2011 Mar 30;11:28
pubmed: 21447194
Genes Dev. 1991 Sep;5(9):1513-23
pubmed: 1653172
Proc Natl Acad Sci U S A. 1989 Apr;86(8):2698-702
pubmed: 2539597
Sci Rep. 2018 Dec 14;8(1):17882
pubmed: 30552368
Gene. 1996 Jun 1;171(2):197-201
pubmed: 8666272
J Mol Biol. 1984 Sep 15;178(2):481-6
pubmed: 6333513
Dev Dyn. 2020 Mar;249(3):342-353
pubmed: 31386776
Development. 1993 Jun;118(2):401-15
pubmed: 8223268
Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5172-7
pubmed: 9560248
Nat Commun. 2017 Dec 22;8(1):2286
pubmed: 29273779
Science. 1934 Dec 28;80(2087):620-1
pubmed: 17809156
Genome Res. 2014 Jan;24(1):142-53
pubmed: 24179142
Nat Commun. 2014 Dec 01;5:5661
pubmed: 25434971
Dev Biol. 2017 Feb 15;422(2):155-170
pubmed: 28017643
Dev Dyn. 1994 Aug;200(4):278-93
pubmed: 7994075
Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15008-13
pubmed: 17005721
Elife. 2020 Mar 06;9:
pubmed: 32142407
Gene. 1999 Nov 15;240(1):239-44
pubmed: 10564832
Genesis. 2012 Aug;50(8):642-50
pubmed: 22422643
Nature. 2010 Mar 25;464(7288):606-9
pubmed: 20336145
Dev Dyn. 2007 Apr;236(4):1025-35
pubmed: 17326133
Dev Dyn. 2009 Jul;238(7):1727-43
pubmed: 19517568
Nat Protoc. 2014 Mar;9(3):529-40
pubmed: 24504478