Bioinspired self-degradable hydrogels towards wound sealing.


Journal

Biomaterials science
ISSN: 2047-4849
Titre abrégé: Biomater Sci
Pays: England
ID NLM: 101593571

Informations de publication

Date de publication:
18 May 2021
Historique:
pubmed: 6 5 2021
medline: 21 5 2021
entrez: 5 5 2021
Statut: ppublish

Résumé

Inspired by the autolysis of shaggy mane, we developed a self-degradable hydrogel as a medical adhesive for skin wounds. The rapid gelation and self-degradation of the hydrogel were achieved via the Michael addition and subsequent hydrolysis of the addition product. In vivo experiments further showed that the hydrogel adhesive was efficiently applied for skin wound repair.

Identifiants

pubmed: 33949458
doi: 10.1039/d1bm00420d
doi:

Substances chimiques

Adhesives 0
Hydrogels 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3645-3649

Auteurs

Qingchen Cao (Q)

Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. dcwu@iccas.ac.cn and University of Chinese Academy of Sciences, Beijing 100049, China. wangxing@iccas.ac.cn.

Guofei Sun (G)

Department of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China. zhanglcheng218@126.com.

Xing Wang (X)

Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. dcwu@iccas.ac.cn and University of Chinese Academy of Sciences, Beijing 100049, China. wangxing@iccas.ac.cn.

Fei Yang (F)

Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. dcwu@iccas.ac.cn and University of Chinese Academy of Sciences, Beijing 100049, China. wangxing@iccas.ac.cn.

Licheng Zhang (L)

Department of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China. zhanglcheng218@126.com.

Decheng Wu (D)

Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. dcwu@iccas.ac.cn and Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.

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Classifications MeSH