Binge-Like Ethanol Drinking Increases
Alcohol use disorder
Mdk
Otx2
Wnt1
dopamine
ethanol
mouse
Journal
Neuroscience insights
ISSN: 2633-1055
Titre abrégé: Neurosci Insights
Pays: United States
ID NLM: 101760670
Informations de publication
Date de publication:
2021
2021
Historique:
received:
29
12
2020
accepted:
25
03
2021
entrez:
6
5
2021
pubmed:
7
5
2021
medline:
7
5
2021
Statut:
epublish
Résumé
Alcohol use disorder is associated with pathophysiological changes in the dopaminergic system. Orthodenticle homeobox 2 (OTX2) is a transcription factor important for the development of dopaminergic neurons residing in the ventral tegmental area (VTA), a critical region of the brain involved in drug reinforcement. Previous studies have demonstrated that ethanol exposure during embryonic development reduces
Identifiants
pubmed: 33954290
doi: 10.1177/26331055211009850
pii: 10.1177_26331055211009850
pmc: PMC8058803
doi:
Types de publication
Journal Article
Langues
eng
Pagination
26331055211009850Subventions
Organisme : NIAAA NIH HHS
ID : P50 AA022538
Pays : United States
Organisme : NIAAA NIH HHS
ID : U01 AA020912
Pays : United States
Informations de copyright
© The Author(s) 2021.
Déclaration de conflit d'intérêts
Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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