The road to zero nosocomial infections in neonates-a narrative review.

neonates nosocomial infections quality improvement

Journal

Acta paediatrica (Oslo, Norway : 1992)
ISSN: 1651-2227
Titre abrégé: Acta Paediatr
Pays: Norway
ID NLM: 9205968

Informations de publication

Date de publication:
08 2021
Historique:
revised: 08 04 2021
received: 18 02 2021
accepted: 22 04 2021
pubmed: 7 5 2021
medline: 6 8 2021
entrez: 6 5 2021
Statut: ppublish

Résumé

Nosocomial infections (NI) in neonates are associated with prolonged hospitalisation, adverse neurodevelopmental outcome and high mortality. Over the past decade, numerous prevention strategies have resulted in significant reductions in NI rates. In this review, we aim to provide an overview of current NI rates from large, geographically defined cohorts. PubMed, Web of Science, EMBASE and Cochrane Library were searched for evidence regarding epidemiology and prevention of NI in neonates. Extracted studies were synthesised in a narrative form with experiential reflection. Despite the abundance of geographically defined incidence proportions, an epidemiological overview of NI is difficult to provide, given the lack of consensus definition for neonatal NI and different baseline populations being compared. Successful prevention efforts have focused on implementing evidence-based practices while eliminating outdated strategies. The most promising model for reduction in infection rates is based on quality improvement (QI) collaboratives and benchmarking, involving identification and implementation of best practices, selection of measurable outcomes and fostering a sense of community and transparency. The preventative rather than curative approach forms the new paradigm for reducing the burden of neonatal infections. Despite progress achieved, continued work towards improved prevention practices is required in the strive towards zero NIs.

Identifiants

pubmed: 33955065
doi: 10.1111/apa.15886
pmc: PMC8359829
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2326-2335

Informations de copyright

©2021 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

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Auteurs

Sophie J Jansen (SJ)

Division of Neonatology, Department of Pediatrics, Willem Alexander Children's Hospital - Leiden University Medical Center (LUMC), Leiden, The Netherlands.

Enrico Lopriore (E)

Division of Neonatology, Department of Pediatrics, Willem Alexander Children's Hospital - Leiden University Medical Center (LUMC), Leiden, The Netherlands.

Martha T van der Beek (MT)

Department of Medical Microbiology, Leiden University Medical Center (LUMC, Leiden, The Netherlands.

Karin Ellen Veldkamp (KE)

Department of Medical Microbiology, Leiden University Medical Center (LUMC, Leiden, The Netherlands.

Sylke J Steggerda (SJ)

Division of Neonatology, Department of Pediatrics, Willem Alexander Children's Hospital - Leiden University Medical Center (LUMC), Leiden, The Netherlands.

Vincent Bekker (V)

Division of Neonatology, Department of Pediatrics, Willem Alexander Children's Hospital - Leiden University Medical Center (LUMC), Leiden, The Netherlands.

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Classifications MeSH