Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged ≥65 Years - United States, January-March 2021.


Journal

MMWR. Morbidity and mortality weekly report
ISSN: 1545-861X
Titre abrégé: MMWR Morb Mortal Wkly Rep
Pays: United States
ID NLM: 7802429

Informations de publication

Date de publication:
07 May 2021
Historique:
entrez: 6 5 2021
pubmed: 7 5 2021
medline: 8 5 2021
Statut: epublish

Résumé

Adults aged ≥65 years are at increased risk for severe outcomes from COVID-19 and were identified as a priority group to receive the first COVID-19 vaccines approved for use under an Emergency Use Authorization (EUA) in the United States (1-3). In an evaluation at 24 hospitals in 14 states,* the effectiveness of partial or full vaccination

Identifiants

pubmed: 33956782
doi: 10.15585/mmwr.mm7018e1
pmc: PMC9368749
doi:

Substances chimiques

COVID-19 Vaccines 0
Vaccines, Synthetic 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

674-679

Subventions

Organisme : NCIRD CDC HHS
ID : U01 IP000972
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001857
Pays : United States
Organisme : NCIRD CDC HHS
ID : U01 IP000969
Pays : United States
Organisme : NCIRD CDC HHS
ID : U01 IP000974
Pays : United States
Organisme : NIGMS NIH HHS
ID : K23 GM129661
Pays : United States

Investigateurs

Omowunmi Amosu (O)
Brent Armbruster (B)
Valerie Aston (V)
Marianne Bernardo (M)
Robert Bowers (R)
Leslie De Souza (L)
Jennifer Friedel (J)
Kevin Gardner (K)
Jennifer Goff (J)
Alexandra June Gordon (AJ)
Audrey Hendrickson (A)
Madeline Hicks (M)
Michelle Howell (M)
Jakea Johnson (J)
Jeffrey Jorgensen (J)
Sarah Karow (S)
Lori Kozikowski (L)
Olivia Krol (O)
Leigha Landreth (L)
Mary LaRose (M)
Brenda Lopez (B)
New York (N)
Andrea Luong (A)
Bob McClellan (B)
Ellen Maruggi (E)
Karen Miller (K)
Rahul Nair (R)
Lisa Parks (L)
Jennifer Peers (J)
Cynthia Perez (C)
Adreanne Rivera (A)
Jonasel Roque (J)
Andres Santana (A)
Tyler Scharber (T)
Emma Silverman (E)
Michael Tozier (M)
Hiwet Tzehaie (H)
Zachary Zouyed (Z)
Alejandro Arroliga (A)
Alicia Bagiatis (A)
G K Balasubramani (GK)
Caroline K Cheng (CK)
Heather Eng (H)
Shekhar Ghamande (S)
Judy Herrick (J)
Eric Hoffman (E)
Kailey Hughes (K)
Lois E Lamerato (LE)
Adam S Lauring (AS)
Amanda McKillop (A)
Tresa McNeal (T)
E J McSpadden (EJ)
John Midturi (J)
Manohar Mutnal (M)
Mary Patricia Nowalk (MP)
Joshua G Petrie (JG)
Chandni Raiyani (C)
Arundhati Rao (A)
Sean G Saul (SG)
Theresa M Sax (TM)
Hannah E Segaloff (HE)
Lori Stiefel (L)
Marcus Volz (M)
Kimberly Walker (K)
Nicole Wheeler (N)
Heath White (H)
John V Williams (JV)
Mohamed Yassin (M)
Martha Zayed (M)
Tnelda Zunie (T)

Déclaration de conflit d'intérêts

All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Christopher J. Lindsell reports grants from National Institutes of Health, U.S. Department of Defense, Marcus Foundation, Endpoint Health, Entegrion, bioMerieux, and Bioscape Digital, outside the submitted work. Jay S. Steingrub reports grants from National Institutes of Health, outside the submitted work. Akram Khan reports grants from United Therapeutics, Actelion Pharmaceuticals, Regeneron, and Reata Pharmaceuticals, outside the submitted work. Samuel M. Brown reports grants from National Institutes of Health, U.S. Department of Defense, Intermountain Research and Medical Foundation, and Janssen, and consulting fees paid to his employer from Faron and Sedana, all outside the submitted work. Ithan D. Peltan reports grants from National Institutes of Health and, outside the submitted work, grants from Asahi Kasei Pharma, Janssen Pharmaceuticals, and Regeneron. Adit A. Ginde reports grants from National Institutes of Health, U.S. Department of Defense and AbbVie, outside the submitted work. Carlos G. Grijalva reports consulting fees from Pfizer, Merck, and Sanofi-Pasteur, grants from Campbell Alliance/Syneos Health, National Institutes of Health, Food and Drug Administration, and Agency for Health Care Research and Quality, outside the submitted work. Michelle N. Gong reports grants from National Institutes of Health, Agency for Healthcare Research and Quality, and consulting fees from Regeneron, Philips Healthcare, all outside the submitted work. Steven Y. Chang reports consulting fees from PureTech Health and speaker fees from La Jolla Pharmaceuticals, both outside the submitted work. Jonathan D. Casey reports grants from National Institutes of Health, outside the submitted work. Todd W. Rice reports grants from National Institutes of Health and Endpoint Health, consulting work for Cumberland Pharmaceuticals, Inc, and Sanofi, Inc., outside the submitted work. Manjusha Gaglani reports grants from CDC-Abt Associates, outside the submitted work. Emily T. Martin reports personal fees from Pfizer and grants from Merck, outside the submitted work. Anurag Malani reports shareholder of Pfizer pharmaceuticals. Arnold S. Monto reports personal fees from Sanofi Pasteur and Seqirus, outside the submitted work. Fernanda P. Silveira reports grants from Shire, Qiagen, Ansun, and Novartis, outside the submitted work. Richard K. Zimmerman reports grants from Sanofi Pasteur, outside the submitted work. Donald B. Middleton reports grants and personal fees from Pfizer and personal fees from Seqirus, Sanofi Pasteur, and GlaxoSmithKline, outside the submitted work. No other potential conflicts of interest were disclosed.

Références

JAMA. 2020 Nov 17;324(19):1939-1940
pubmed: 33064144
MMWR Morb Mortal Wkly Rep. 2020 Apr 17;69(15):458-464
pubmed: 32298251
N Engl J Med. 2021 Apr 15;384(15):1412-1423
pubmed: 33626250
Vaccine. 2013 Apr 19;31(17):2165-8
pubmed: 23499601
MMWR Morb Mortal Wkly Rep. 2021 Mar 05;70(9):326-328
pubmed: 33661863
N Engl J Med. 2021 Feb 4;384(5):403-416
pubmed: 33378609
MMWR Morb Mortal Wkly Rep. 2021 Jan 01;69(5152):1657-1660
pubmed: 33382671
N Engl J Med. 2020 Dec 31;383(27):2603-2615
pubmed: 33301246
Lancet. 2021 Jan 16;397(10270):220-232
pubmed: 33428867
MMWR Morb Mortal Wkly Rep. 2020 Jul 17;69(28):923-929
pubmed: 32673298

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