Update on management of hypokalaemia and goals for the lower potassium level in patients with cardiovascular disease: a review in collaboration with the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy.


Journal

European heart journal. Cardiovascular pharmacotherapy
ISSN: 2055-6845
Titre abrégé: Eur Heart J Cardiovasc Pharmacother
Pays: England
ID NLM: 101669491

Informations de publication

Date de publication:
03 11 2021
Historique:
received: 27 12 2020
accepted: 04 05 2021
pubmed: 7 5 2021
medline: 31 3 2022
entrez: 6 5 2021
Statut: ppublish

Résumé

Hypokalaemia is common in patients with cardiovascular disease. In this review, we emphasize the importance of tight potassium regulation in patients with cardiovascular disease based on findings from observational studies. To enhance the understanding, we also describe the mechanisms of potassium homeostasis maintenance, the most common causes of hypokalaemia and present strategies for monitoring and management of low potassium levels. We propose elevation of potassium in asymptomatic patients with lower normal concentrations and concurrent cardiovascular disease. These proposals are intended to assist clinicians until more evidence is available.

Identifiants

pubmed: 33956964
pii: 6270921
doi: 10.1093/ehjcvp/pvab038
doi:

Substances chimiques

Potassium RWP5GA015D

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

557-567

Informations de copyright

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2021. For permissions, please email: journals.permissions@oup.com.

Auteurs

Maria Lukács Krogager (ML)

Department of Cardiology, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.

Kristian Kragholm (K)

Department of Cardiology, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Department of Cardiology, Region Hospital North Jutland, Bispensgade 37, 9800, Hjørring, Denmark.
Unit of Epidemiology and Biostatistics, Aalborg University Hospital, Søndre Skovvej 15, 9000, Aalborg, Denmark.

Jesper Qvist Thomassen (JQ)

Department of Clinical Biochemistry, Copenhagen University Hospital (Rigshospitalet), Blegdamsvej 9, 2100, Copenhagen, Denmark.

Peter Søgaard (P)

Department of Cardiology, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.

Basil S Lewis (BS)

Lady Davis Carmel Medical Center, Mikhal St 7, Haifa, Israel.
The Ruth and Bruce Rappaport School of Medicine, Technion-IIT, Haifa, Israel.

Sven Wassmann (S)

Cardiology Pasing, Institutstr. 14, 81241 Munich, Germany.
Department of Cardiology, University of the Saarland, Kirrbergerstr. 100, 66421 Homburg/Saar, Germany.

Iris Baumgartner (I)

Department of Angiology, Bern University Hospital (Inselspital), Hochschulstrasse 4, 3012, Bern, Switzerland.

Claudio Ceconi (C)

Department of Cardiology, Desenzano Del Garda Hospital, Monte Croce, 25015, Desenzano del Garda, Italy.

Thomas Andersen Schmidt (TA)

Institute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Nørregade 10, 2100, Copenhagen, Denmark.
The Emergency Department, North Zealand University Hospital, Dyrhavevej 29, 3400, Hillerød, Denmark.

Juan Carlos Kaski (JC)

Molecular and Clinical Sciences Research Institute, St George's, University of London, Cranmer Terrace London SW17 0RE, London, UK.

Heinz Drexel (H)

Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Landeskrankenhaus, Carinagasse 47 A, 6800, Feldkirch, Austria.
Private University of the Principality of Liechtenstein, Dorfstrasse 24 FL, 9495, Triesen, Liechtenstein.
Drexel University College of Medicine, 2900 W. Queen Lane Philadelphia, PA 19129, USA.

Anne Grete Semb (AG)

Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Reidar Kobros Vei 5, 0370, Oslo, Norway.

Stefan Agewall (S)

Department of Cardiology, Ullevål, Oslo University Hospital, Kirkeveien 166, 0450, Oslo, Norway.
Institute of Clinical Sciences, Søsterhjemmet, University of Oslo, Kirkeveien 166, 2nd floor, 0450, Oslo, Norway.

Alexander Niessner (A)

Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Spitalgasse 23, 1090, Vienna, Austria.

Gianluigi Savarese (G)

Division of Cardiology, Department of Medicine, Karolinska Instituttet, Nobels väg 5, 171 77, Solna, Stockholm, Sweden.

Keld Per Kjeldsen (KP)

Department of Cardiology, Copenhagen University Hospital (Amager-Hvidovre), Kettegård Alle 30, 2650 Hvidovre, Copenhagen, Denmark.
Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Fredrik Bajers Vej 7C, 9200, Aalborg, Denmark.

Claudio Borghi (C)

Department of Medical and Surgical Sciences, University of Bologna, Via Zamboni, 33 - 40126, Bologna, Italy.

Juan Tamargo (J)

Department of Pharmacology, School of Medicine, CIBERCV, University Complutense, Avda. de Séneca, 2 Ciudad Universitaria, 28040 Madrid, Spain.

Christian Torp-Pedersen (C)

Department of Clinical Research, North Zealand University Hospital, Dyrehavevej 48, 3400, Hillerød, Denmark.

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Classifications MeSH