Phenomenological model of auditory nerve population responses to cochlear implant stimulation.
Accommodation
Auditory nerve fiber population
Cochlear implant
Facilitation
Phenomenological model
Spatial spread
Journal
Journal of neuroscience methods
ISSN: 1872-678X
Titre abrégé: J Neurosci Methods
Pays: Netherlands
ID NLM: 7905558
Informations de publication
Date de publication:
01 07 2021
01 07 2021
Historique:
received:
14
08
2020
revised:
26
04
2021
accepted:
29
04
2021
pubmed:
7
5
2021
medline:
1
7
2021
entrez:
6
5
2021
Statut:
ppublish
Résumé
Models of auditory nerve fiber (ANF) responses to electrical stimulation are helpful to develop advanced coding for cochlear implants (CIs). A phenomenological model of ANF population responses to CI electrical stimulation with a lower computational complexity compared to a biophysical model would be beneficial to evaluate new CI coding strategies. This study presents a phenomenological model which combines four temporal characteristics of ANFs (refractoriness, facilitation, accommodation and spike rate adaptation) in addition to a spatial spread of the electric field. The model predicts the performances of CI subjects in the melodic contour identification (MCI) experiment. The simulations for the MCI experiment were consistent with CI recipients' experimental outcomes that were not predictable from the electrical stimulation patterns themselves. Previously, no phenomenological population model of ANFs has combined all four aforementioned temporal phenomena. The proposed model would help the further investigations of ANFs responses to different electrical stimulation patterns and comparison of different sound coding strategies in CIs.
Sections du résumé
BACKGROUND
Models of auditory nerve fiber (ANF) responses to electrical stimulation are helpful to develop advanced coding for cochlear implants (CIs). A phenomenological model of ANF population responses to CI electrical stimulation with a lower computational complexity compared to a biophysical model would be beneficial to evaluate new CI coding strategies.
NEW METHOD
This study presents a phenomenological model which combines four temporal characteristics of ANFs (refractoriness, facilitation, accommodation and spike rate adaptation) in addition to a spatial spread of the electric field.
RESULTS
The model predicts the performances of CI subjects in the melodic contour identification (MCI) experiment. The simulations for the MCI experiment were consistent with CI recipients' experimental outcomes that were not predictable from the electrical stimulation patterns themselves.
COMPARISON WITH EXISTING METHODS
Previously, no phenomenological population model of ANFs has combined all four aforementioned temporal phenomena.
CONCLUSIONS
The proposed model would help the further investigations of ANFs responses to different electrical stimulation patterns and comparison of different sound coding strategies in CIs.
Identifiants
pubmed: 33957156
pii: S0165-0270(21)00147-3
doi: 10.1016/j.jneumeth.2021.109212
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
109212Informations de copyright
Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.