Interplay Between Cognitive and Bowel/Bladder Function in Multiple Sclerosis.
Bladder
Bowel
Cognition
Disability
Patient-Reported Outcome
Journal
International neurourology journal
ISSN: 2093-4777
Titre abrégé: Int Neurourol J
Pays: Korea (South)
ID NLM: 101534513
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
21
09
2020
accepted:
29
11
2020
pubmed:
7
5
2021
medline:
7
5
2021
entrez:
6
5
2021
Statut:
ppublish
Résumé
The aim of this study was to evaluate the prevalence of bowel/bladder dysfunction in multiple sclerosis (MS) and its associations with cognitive impairment. We prospectively enrolled 150 MS patients. Patients were administered the Symbol Digit Modality Test (SDMT), the Neurogenic Bowel Dysfunction Score (NBDS), and the Actionable Bladder Symptom Screening Tool (ABSST). The associations between bowel/bladder dysfunction and cognitive function were assessed through hierarchical regression models using the SDMT and clinicodemographic features as independent variables and NBDS and ABSST scores as dependent variables. The prevalence of bowel/bladder deficits was 44.7%, with 26 patients (17.3%) suffering from bowel deficits and 60 patients (40%) from bladder deficits. The total NBDS and ABSST scores were correlated with the SDMT (β=-0.10, P<0.001 and β=-0.03, P=0.04, respectively) after correction for demographic features and physical disability. Bowel/bladder disorders are common in MS and are associated with both physical and cognitive disability burdens. As SDMT is embedded into routine clinical assessments, a lower score may warrant investigating bowel/bladder dysfunction due to the strong interplay of these factors.
Identifiants
pubmed: 33957715
pii: inj.2040346.173
doi: 10.5213/inj.2040346.173
pmc: PMC8748300
doi:
Types de publication
Journal Article
Langues
eng
Pagination
310-318Subventions
Organisme : Almirall
Organisme : ECTRIMS-MAGNIMS Society
Organisme : UK MS Society
Organisme : Merck
Organisme : Novartis
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