The Efficacy of Intraoperative Fluorescent Imaging Using Indocyanine Green for Cholangiography During Cholecystectomy and Hepatectomy.
indocyanine green fluorescent imaging
navigation surgery
near-infrared fluorescent cholangiography
Journal
Clinical and experimental gastroenterology
ISSN: 1178-7023
Titre abrégé: Clin Exp Gastroenterol
Pays: New Zealand
ID NLM: 101532800
Informations de publication
Date de publication:
2021
2021
Historique:
received:
10
08
2020
accepted:
06
04
2021
entrez:
7
5
2021
pubmed:
8
5
2021
medline:
8
5
2021
Statut:
epublish
Résumé
Bile duct injury is one of the most serious complications of laparoscopic cholecystectomy. Intraoperative indocyanine green (ICG) cholangiography is a safe and useful navigation modality for confirming the biliary anatomy. ICG cholangiography is expected to be a routine method for helping avoid bile duct injuries. We examined 25 patients who underwent intraoperative cholangiography using ICG fluorescence. Two methods of ICG injection are used: intrabiliary injection (percutaneous transhepatic gallbladder drainage [PTGBD], gallbladder [GB] puncture and endoscopic nasobiliary drainage [ENBD]) at a dosage of 0.025 mg during the operation or intravenous injection with 2.5 mg ICG preoperatively. There were 24 patients who underwent laparoscopic cholecystectomy and 1 patient who underwent hepatectomy. For laparoscopic cholecystectomy, the average operation time was 127 (50-197) minutes, and estimated blood loss was 43.2 (0-400) g. The ICG administration route was intravenous injections in 12 cases and intrabiliary injection in 12 cases (GB injection: 3 cases, PTGBD: 8 cases, ENBD:1 case). The course of the biliary tree was able to be confirmed in all cases that received direct injection into the biliary tract, whereas bile structures were recognizable in only 10 cases (83.3%) with intravenous injection. The postoperative hospital stay was 4.6 (3-9) days, and no postoperative complications (Clavien-Dindo ≧IIIa) were observed. For hepatectomy, a tumor located near the left Glissonian pedicle was resected using a fluorescence image guide. Biliary structures were fluorescent without injury after resecting the tumor. No adverse events due to ICG administration were observed, and the procedure was able to be performed safely. ICG fluorescence imaging allows surgeons to visualize the course of the biliary tree in real time during cholecystectomy and hepatectomy. This is considered essential for hepatobiliary surgery to prevent biliary tree injury and ensure safe surgery.
Identifiants
pubmed: 33958888
doi: 10.2147/CEG.S275985
pii: 275985
pmc: PMC8096340
doi:
Types de publication
Journal Article
Langues
eng
Pagination
145-154Informations de copyright
© 2021 Shibata et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
Références
Langenbecks Arch Surg. 2018 Aug;403(5):671-680
pubmed: 29915961
World J Gastroenterol. 2015 Jul 7;21(25):7877-83
pubmed: 26167088
J Am Coll Surg. 1995 Jan;180(1):101-25
pubmed: 8000648
J Am Coll Surg. 2003 Mar;196(3):385-93
pubmed: 12648690
Surg Endosc. 2015 Jun;29(6):1621-6
pubmed: 25277476
World J Surg. 2015 Jul;39(7):1798-803
pubmed: 25711485
J Am Coll Surg. 2015 Dec;221(6):e113-7
pubmed: 26412565
Surg Laparosc Endosc Percutan Tech. 2012 Aug;22(4):341-4
pubmed: 22874684
J Am Coll Surg. 2009 Jan;208(1):e1-4
pubmed: 19228492
Ann Surg. 2001 Feb;233(2):221-6
pubmed: 11176128
Surg Endosc. 2014 Jun;28(6):1838-43
pubmed: 24414461
Langenbecks Arch Surg. 2020 Sep;405(6):827-832
pubmed: 32827267
Obes Surg. 2016 Mar;26(3):525-30
pubmed: 26224370
Ann Surg. 2017 Nov;266(5):890-897
pubmed: 28742709
JSLS. 2005 Jan-Mar;9(1):51-7
pubmed: 15791971
Surg Endosc. 2013 Jun;27(6):2156-62
pubmed: 23271272
World J Surg. 2010 Feb;34(2):336-43
pubmed: 20033407
Surg Innov. 2014 Dec;21(6):615-21
pubmed: 24616013
J Hepatobiliary Pancreat Sci. 2010 Sep;17(5):590-4
pubmed: 19844652
Ann Surg. 2003 Apr;237(4):460-9
pubmed: 12677139
J Laparoendosc Adv Surg Tech A. 2015 Jun;25(6):486-92
pubmed: 25974072
Surg Endosc. 2020 May;34(5):1959-1967
pubmed: 31309307
J Hepatobiliary Pancreat Sci. 2013 Jan;20(1):8-23
pubmed: 23307004
Surg Endosc. 2015 Feb;29(2):368-75
pubmed: 24986018
Dan Med J. 2014 Aug;61(8):A4891
pubmed: 25162446
Arch Surg. 2006 Dec;141(12):1207-13
pubmed: 17178963
Br J Surg. 2006 Feb;93(2):158-68
pubmed: 16432812
J Hepatobiliary Pancreat Surg. 2002;9(5):592-9
pubmed: 12541045
J Laparoendosc Adv Surg Tech A. 2017 Oct;27(10):1069-1073
pubmed: 28574801
Ann Surg. 2019 Dec;270(6):992-999
pubmed: 30614881
World J Surg. 2008 Aug;32(8):1763-7
pubmed: 18543027
Am J Surg. 2016 May;211(5):933-7
pubmed: 27151917
Arch Surg. 2009 Apr;144(4):381-2
pubmed: 19380655
Surg Endosc. 2018 Mar;32(3):1506-1514
pubmed: 28916859
J Hepatobiliary Pancreat Sci. 2021 Feb;28(2):202-210
pubmed: 33091224
Ann Surg Oncol. 2006 Dec;13(12):1671-81
pubmed: 17009138
Surg Endosc. 2015 Jul;29(7):2046-55
pubmed: 25303914
Br J Surg. 2010 Sep;97(9):1369-77
pubmed: 20623766
Surg Endosc. 2017 Jun;31(6):2483-2490
pubmed: 27778170
Endoscopy. 2015 Jan;47(1):40-6
pubmed: 25532112