Heart Transplantation in Mustard Patients Bridged With Continuous Flow Systemic Ventricular Assist Device - A Case Report and Review of Literature.

d-TGA heart transplantation mustard procedure pulmonary hypertension pulmonary hypertension reversal transposition of the great arteries ventricular assist device

Journal

Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388

Informations de publication

Date de publication:
2021
Historique:
received: 10 01 2021
accepted: 24 03 2021
entrez: 7 5 2021
pubmed: 8 5 2021
medline: 8 5 2021
Statut: epublish

Résumé

Thirty four-year-old male with history of D-transposition of the great arteries (D-TGA) who underwent Mustard operation at 14 months of age presented in cardiogenic shock secondary to severe systemic right ventricular failure. Catheterization revealed significantly increased pulmonary pressures. Due to the patient's inotrope dependence and prohibitive pulmonary hypertension, he underwent implantation of a Heart Ware HVAD® for systemic RV support. Within 4 months of continuous flow ventricular assist device (VAD) implantation complete normalization of pulmonary vascular resistance (PVR) was achieved. He ultimately underwent orthotopic heart transplantation with favorable outcomes. This is the second report of complete normalization of PVR following VAD implantation into a systemic RV in <4 months. We conducted a thorough literature review to identify Mustard patients that received systemic RV VAD as a bridge to a successful heart transplantation. In this article, we summarize the outcomes and focus on pulmonary hypertension reversibility following VAD implant.

Identifiants

pubmed: 33959642
doi: 10.3389/fcvm.2021.651496
pmc: PMC8093374
doi:

Types de publication

Case Reports

Langues

eng

Pagination

651496

Informations de copyright

Copyright © 2021 Bou Chaaya, Simon, Turrentine, Herrmann, Kay, Guglin, Saleem and Rao.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Rody G Bou Chaaya (RG)

Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States.

Joel W Simon (JW)

Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, IN, United States.

Mark Turrentine (M)

Division of Pediatric Cardiothoracic Surgery, Riley Hospital for Children, Indianapolis, IN, United States.

Jeremy L Herrmann (JL)

Division of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States.

William Aaron Kay (WA)

Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, IN, United States.

Maya Guglin (M)

Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, IN, United States.

Kashif Saleem (K)

Division of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, IN, United States.

Roopa A Rao (RA)

Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, IN, United States.

Classifications MeSH