c-Rel employs multiple mechanisms to promote the thymic development and peripheral function of regulatory T cells in mice.
Cell cycle progression
Regulatory T cells
Thymic development
c-Rel
Journal
European journal of immunology
ISSN: 1521-4141
Titre abrégé: Eur J Immunol
Pays: Germany
ID NLM: 1273201
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
revised:
12
03
2021
received:
23
07
2020
accepted:
05
05
2021
pubmed:
8
5
2021
medline:
8
10
2021
entrez:
7
5
2021
Statut:
ppublish
Résumé
The NF-κB transcription factor c-Rel is a critical regulator of Treg ontogeny, controlling multiple points of the stepwise developmental pathway. Here, we found that the thymic Treg defect in c-Rel-deficient (cRel
Identifiants
pubmed: 33960413
doi: 10.1002/eji.202048900
doi:
Substances chimiques
Proto-Oncogene Proteins c-rel
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2006-2026Subventions
Organisme : NCI NIH HHS
ID : R01 CA157660
Pays : United States
Informations de copyright
© 2021 Wiley-VCH GmbH.
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