IDH-mutant brainstem gliomas in adolescent and young adult patients: Report of three cases and review of the literature.
IDH
brain biopsy
brainstem glioma
isocitrate dehydrogenase
low grade glioma
young adult
Journal
Brain pathology (Zurich, Switzerland)
ISSN: 1750-3639
Titre abrégé: Brain Pathol
Pays: Switzerland
ID NLM: 9216781
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
received:
05
02
2021
accepted:
23
03
2021
pubmed:
8
5
2021
medline:
3
2
2022
entrez:
7
5
2021
Statut:
ppublish
Résumé
Isocitrate dehydrogenase (IDH) mutations are rare in pediatric and adolescent gliomas. We recently identified three adolescent/young adult (AYA) patients with IDH-mutant low grade gliomas of the brainstem with several key clinicopathologic and molecular features in common. We discuss these three cases and review the current literature.
Identifiants
pubmed: 33960568
doi: 10.1111/bpa.12959
pmc: PMC8412065
doi:
Substances chimiques
Isocitrate Dehydrogenase
EC 1.1.1.41
Types de publication
Case Reports
Letter
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e12959Informations de copyright
© 2021 The Authors. Brain Pathology published by John Wiley & Sons Ltd on behalf of International Society of Neuropathology.
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