Prehemodialysis hyponatremia and extracellular water: Is it simply too much water?


Journal

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
ISSN: 1744-9987
Titre abrégé: Ther Apher Dial
Pays: Australia
ID NLM: 101181252

Informations de publication

Date de publication:
Feb 2022
Historique:
revised: 16 04 2021
received: 01 03 2021
accepted: 04 05 2021
pubmed: 8 5 2021
medline: 11 2 2022
entrez: 7 5 2021
Statut: ppublish

Résumé

Observational hemodialysis (HD) studies report an association between hyponatremia and increased mortality. As volume overload is also associated with mortality, we wished to determine whether hyponatremia is linked to increased extracellular water (ECW). We measured ECW, total body water (TBW) and body composition predialysis with multifrequency bioimpedance, arm strength with pinch gauge and hand grip strength (PS, HGS), standard biochemistry profiles, comorbidity and clinical frailty scores (CFS). We reviewed 324 patients, 195 (60.2%) male, mean age 62.3 ± 15.6 years. Thirty-eight (11.7%) patients were hyponatremic (sodium ≤135 mmol/L), ECW/height

Identifiants

pubmed: 33960683
doi: 10.1111/1744-9987.13685
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

154-161

Informations de copyright

© 2021 International Society for Apheresis, Japanese Society for Apheresis, and Japanese Society for Dialysis Therapy.

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Auteurs

Roohi Chhabra (R)

UCL Department of Nephrology, Royal Free Hospital, London, UK.

Andrew Davenport (A)

UCL Department of Nephrology, University College London, London, UK.

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