Auditory brainstem response asymmetries in older adults: An exploratory study using click and speech stimuli.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2021
2021
Historique:
received:
23
05
2019
accepted:
25
04
2021
entrez:
7
5
2021
pubmed:
8
5
2021
medline:
25
2
2023
Statut:
epublish
Résumé
Some evidence suggests that young adults exhibit a selective laterality of auditory brainstem response (ABR) elicited with speech stimuli. Little is known about such an auditory laterality in older adults. The aim of this study was to investigate possible asymmetric auditory brainstem processing between right and left ear presentation in older adults. Sixty-two older adults presenting with normal hearing thresholds according to their age and who were native speakers of Quebec French participated in this study. ABR was recorded using click and a 40-ms /da/ syllable. ABR was elicited through monaural right and monaural left stimulation. Latency and amplitude for click-and speech-ABR components were compared between right and left ear presentations. In addition, for the /da/ syllable, a fast Fourier transform analysis of the sustained frequency-following response (FFR) of the vowel was performed along with stimulus-to-response and right-left ear correlation analyses. No significant differences between right and left ear presentation were found for amplitudes and latencies of the click-ABR components. Significantly shorter latencies for right ear presentation as compared to left ear presentation were observed for onset and offset transient components (V, A and O), sustained components (D and E), and voiced transition components (C) of the speech-ABR. In addition, the spectral amplitude of the fundamental frequency (F0) was significantly larger for the left ear presentation than the right ear presentation. Results of this study show that older adults with normal hearing exhibit symmetric encoding for click stimuli at the brainstem level between the right and left ear presentation. However, they present with brainstem asymmetries for the encoding of selective stimulus components of the speech-ABR between the right and left ear presentation. The right ear presentation of a /da/ syllable elicited reduced neural timing for both transient and sustained components compared to the left ear. Conversely, a stronger left ear F0 encoding was observed. These findings suggest that at a preattentive, sensory stage of auditory processing, older adults lateralize speech stimuli similarly to young adults.
Sections du résumé
BACKGROUND
Some evidence suggests that young adults exhibit a selective laterality of auditory brainstem response (ABR) elicited with speech stimuli. Little is known about such an auditory laterality in older adults.
OBJECTIVE
The aim of this study was to investigate possible asymmetric auditory brainstem processing between right and left ear presentation in older adults.
METHODS
Sixty-two older adults presenting with normal hearing thresholds according to their age and who were native speakers of Quebec French participated in this study. ABR was recorded using click and a 40-ms /da/ syllable. ABR was elicited through monaural right and monaural left stimulation. Latency and amplitude for click-and speech-ABR components were compared between right and left ear presentations. In addition, for the /da/ syllable, a fast Fourier transform analysis of the sustained frequency-following response (FFR) of the vowel was performed along with stimulus-to-response and right-left ear correlation analyses.
RESULTS
No significant differences between right and left ear presentation were found for amplitudes and latencies of the click-ABR components. Significantly shorter latencies for right ear presentation as compared to left ear presentation were observed for onset and offset transient components (V, A and O), sustained components (D and E), and voiced transition components (C) of the speech-ABR. In addition, the spectral amplitude of the fundamental frequency (F0) was significantly larger for the left ear presentation than the right ear presentation.
CONCLUSIONS
Results of this study show that older adults with normal hearing exhibit symmetric encoding for click stimuli at the brainstem level between the right and left ear presentation. However, they present with brainstem asymmetries for the encoding of selective stimulus components of the speech-ABR between the right and left ear presentation. The right ear presentation of a /da/ syllable elicited reduced neural timing for both transient and sustained components compared to the left ear. Conversely, a stronger left ear F0 encoding was observed. These findings suggest that at a preattentive, sensory stage of auditory processing, older adults lateralize speech stimuli similarly to young adults.
Identifiants
pubmed: 33961673
doi: 10.1371/journal.pone.0251287
pii: PONE-D-19-14654
pmc: PMC8104406
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0251287Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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