A review on the applications of electrospun chitosan nanofibers for the cancer treatment.
Cancer treatment
Chitosan nanofibers
Electrospinning
Journal
International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578
Informations de publication
Date de publication:
31 Jul 2021
31 Jul 2021
Historique:
received:
25
03
2021
revised:
24
04
2021
accepted:
01
05
2021
pubmed:
10
5
2021
medline:
27
7
2021
entrez:
9
5
2021
Statut:
ppublish
Résumé
In recent years, the incidence of cancer is increasing every day due to poor quality of life (industrialization of life). Therefore, the treatment of cancer has received much attention from therapists. So far, many anticancer drugs have been used to treat cancer patents. However, the direct use of the anticancer drugs has the adverse side effects for patents and several limitations to treat process. Natural chitosan nanofibers prepared by electrospinning method have unique properties such as high surface area, high porosity, suitable mechanical properties, nontoxicity, biocompatibility, biodegradability, biorenewable, low immunogenicity, better clinical functionality, analogue to extracellular model, and easy production in large scale. Therefore, this bio-polymer is a very suitable case to deliver of the anti-cancer drugs to treat cancer patents. In this review summarizes the electrospinning synthesis of chitosan and its therapeutic application for the various cancer treatment.
Identifiants
pubmed: 33965480
pii: S0141-8130(21)00978-8
doi: 10.1016/j.ijbiomac.2021.05.009
pii:
doi:
Substances chimiques
Antineoplastic Agents
0
Chitosan
9012-76-4
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
790-810Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.