The chemistry and biology of phosphatidylinositol 4-phosphate at the plasma membrane.

GPCR signaling Genetically encoded biosensors Lipid kinase inhibitors PI(4)P PI4KIIIα Phosphoinositides Phospholipid transport

Journal

Bioorganic & medicinal chemistry
ISSN: 1464-3391
Titre abrégé: Bioorg Med Chem
Pays: England
ID NLM: 9413298

Informations de publication

Date de publication:
15 06 2021
Historique:
received: 22 03 2021
revised: 24 04 2021
accepted: 26 04 2021
pubmed: 10 5 2021
medline: 3 11 2021
entrez: 9 5 2021
Statut: ppublish

Résumé

Phosphoinositides are an important class of anionic, low abundance signaling lipids distributed throughout intracellular membranes. The plasma membrane contains three phosphoinositides: PI(4)P, PI(4,5)P

Identifiants

pubmed: 33965837
pii: S0968-0896(21)00198-X
doi: 10.1016/j.bmc.2021.116190
pmc: PMC8169619
mid: NIHMS1702260
pii:
doi:

Substances chimiques

Phosphatidylinositol Phosphates 0
phosphatidylinositol 4-phosphate 0
1-Phosphatidylinositol 4-Kinase EC 2.7.1.67

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

116190

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM131101
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

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Auteurs

Alex G Batrouni (AG)

Department of Chemistry and Chemical Biology and Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.

Jeremy M Baskin (JM)

Department of Chemistry and Chemical Biology and Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA. Electronic address: jeremy.baskin@cornell.edu.

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Classifications MeSH