Innovative diagnostic approach and investigation trends in COVID19-A systematic review.
Angiotensin-converting enzyme type 2
COVID-19
coronavirus
reverse transcription polymerase chain reaction
serological antibodies
Journal
Journal of oral and maxillofacial pathology : JOMFP
ISSN: 0973-029X
Titre abrégé: J Oral Maxillofac Pathol
Pays: India
ID NLM: 101227995
Informations de publication
Date de publication:
Historique:
received:
24
09
2020
revised:
14
12
2020
accepted:
20
10
2020
entrez:
10
5
2021
pubmed:
11
5
2021
medline:
11
5
2021
Statut:
ppublish
Résumé
A highly contagious viral infection emerged in Wuhan city; China had increased mortality with uncertain pathogenesis spreads throughout the world to become a pandemic. It is reported to be caused by a member of β coronaviruses and named it as COVID-19 by the World Health Organization (WHO). The disease is caused by a mutant strain of coronavirus SARS-COV-2 that affects the respiratory tract causing mild to severe respiratory tract illness. The clinical manifestation ranges from mild, moderate, severe and very severe signs and symptoms result in death due to severe hypoxia or multi-organ dysfunction. Also, the affected persons were capable of infecting others through various modes of transmission through respiratory droplets (aerosol spread). A definite investigation protocol has followed to diagnose COVID 19 disease but mainly confirmed with reverse transcription polymerase chain reaction. Computerized tomography scan plays a significant role in the diagnosis and prognosis of affected individuals. The major problem with COVID-19 is due to its novelty and lack of vaccination or treatment. This review focuses on the mutation, pathogenesis, various diagnostic tests adopted and autopsy findings in patients affected with COVID-19.
Identifiants
pubmed: 33967476
doi: 10.4103/jomfp.jomfp_395_20
pii: JOMFP-24-421
pmc: PMC8083432
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
421-436Informations de copyright
Copyright: © 2021 Journal of Oral and Maxillofacial Pathology.
Déclaration de conflit d'intérêts
All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Dr. Beryl Rachel. J, Dr. N. Gururaj, Dr.T,Smitha, Dr. Divyna Daniel. T, Dr. B.S. Harishini and Dr.Adlin Saroja Rosaian. The first draft of the manuscript was written by Dr. Beryl Rachel. J, Dr. Divyna Daniel. T, Dr. B.S. Harishini Dr. N. Gururaj and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript. All the authors agree to be accountable for all aspects of the work in ensuring that question related to accuracy or integrity of any part of the work are appropriately investigated and resolved.
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