Guillain-Barre syndrome in 220 patients with COVID-19.

COVID-19 Guillain-Barre syndrome Immunoglobulins Nerve conduction SARS-CoV-2

Journal

The Egyptian journal of neurology, psychiatry and neurosurgery
ISSN: 1110-1083
Titre abrégé: Egypt J Neurol Psychiatr Neurosurg
Pays: England
ID NLM: 0043617

Informations de publication

Date de publication:
2021
Historique:
received: 05 01 2021
accepted: 23 04 2021
entrez: 10 5 2021
pubmed: 11 5 2021
medline: 11 5 2021
Statut: ppublish

Résumé

This review summarises and discusses recent findings concerning the pathophysiology, clinical presentation, diagnosis, treatment, and outcome of SARS-CoV-2-associated Guillain-Barre syndrome (SC2-GBS). By the end of December 2020, at least 220 patients with SC2-GBS have been published in 95 papers. SC2-GBS is most likely secondary due to an immune reaction against SARS-CoV-2 since the virus has not been found in the CSF of any SC2-GBS patient so far reported. SC2-GBS occurs in each age group and does not differ from non-SC2-GBS regarding clinical presentation and treatment, but the outcome of SC2-GBS is worse compared to non-CS2-GBS patients, and the prevalence/incidence of GBS most likely increased since the outbreak of the pandemic. Early diagnosis of SC2-GBS is warranted to apply appropriate treatment in due time and to improve the overall outcome from the infection.

Identifiants

pubmed: 33967575
doi: 10.1186/s41983-021-00310-7
pii: 310
pmc: PMC8094972
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

55

Commentaires et corrections

Type : CommentIn

Informations de copyright

© The Author(s) 2021.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare that they have no competing interests.

Références

Rev Neurol. 2003 Mar 16-31;36(6):523-6
pubmed: 12652413
Mod Rheumatol. 2009;19(2):199-203
pubmed: 18987779
Eur J Neurol. 2021 Jan;28(1):e10-e12
pubmed: 32978857
J Int Assoc Physicians AIDS Care (Chic). 2007 Sep;6(3):155
pubmed: 17766779
J Med Virol. 2020 Oct;92(10):1845-1857
pubmed: 32492193
Muscle Nerve. 2016 Mar;53(3):384-7
pubmed: 26185107
Brain. 2021 Mar 3;144(2):682-693
pubmed: 33313649
Neurol Sci. 2020 Nov;41(11):3039-3056
pubmed: 32935156
Indian J Crit Care Med. 2020 Jul;24(7):565-569
pubmed: 32963441
J Neurol Neurosurg Psychiatry. 2020 Nov 6;:
pubmed: 33158914

Auteurs

Josef Finsterer (J)

Klinik Landstrasse, Messerli Institute, Postfach 20, 1180 Vienna, Austria.

Fulvio A Scorza (FA)

Disciplina de Neurociência. Universidade Federal de São Paulo/Escola Paulista de Medicina (UNIFESP/EPM), São Paulo, Brazil.

Classifications MeSH