Flow Cytometry in the Diagnosis of Canine T-Cell Lymphoma.

T-cell diagnosis dog flow cytometry lymphoma prognosis

Journal

Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658

Informations de publication

Date de publication:
2021
Historique:
received: 31 08 2020
accepted: 26 02 2021
entrez: 10 5 2021
pubmed: 11 5 2021
medline: 11 5 2021
Statut: epublish

Résumé

T cell lymphoma (TCL) is a heterogenous group of lymphoid malignancies representing about 30-40% of all canine lymphomas and often harboring a very aggressive behavior. WHO classification identifies the majority of TCLs as peripheral TCL, but other subtypes with peculiar presentation and outcome have been recognized. This review aims to explore the use of flow cytometry for refining the diagnosis of canine TCL, putting a particular emphasis on the identification of some peculiar immunotypes, such as T zone lymphoma; on the investigation of putative prognostic markers; and on the evaluation of lymphoma stage and of the minimal residual disease.

Identifiants

pubmed: 33969027
doi: 10.3389/fvets.2021.600963
pmc: PMC8096896
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

600963

Informations de copyright

Copyright © 2021 Comazzi and Riondato.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Stefano Comazzi (S)

Dipartimento di Medicina Veterinaria, Università degli Studi di Milano, Lodi, Italy.

Fulvio Riondato (F)

Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Grugliasco, Italy.

Classifications MeSH