Cardiac perfusion by positron emission tomography.
chronic coronary syndromes
coronary artery disease
myocardial blood flow
myocardial perfusion imaging
positron emission tomography
Journal
Clinical physiology and functional imaging
ISSN: 1475-097X
Titre abrégé: Clin Physiol Funct Imaging
Pays: England
ID NLM: 101137604
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
18
01
2021
accepted:
05
05
2021
pubmed:
11
5
2021
medline:
26
10
2021
entrez:
10
5
2021
Statut:
ppublish
Résumé
Myocardial perfusion imaging (MPI) with positron emission tomography (PET) is an established tool for evaluation of obstructive coronary artery disease (CAD). The contemporary 3-dimensional scanner technology and the state-of-the-art MPI radionuclide tracers and pharmacological stress agents, as well as the cutting-edge image reconstruction techniques and data analysis software, have all enabled accurate, reliable and reproducible quantification of absolute myocardial blood flow (MBF), and henceforth calculation of myocardial flow reserve (MFR) in several clinical scenarios. In patients with suspected coronary artery disease, both absolute stress MBF and MFR can identify myocardial territories subtended by epicardial coronary arteries with haemodynamically significant stenosis, as defined by invasive coronary fractional flow reserve measurement. In particular, absolute stress MBF and MFR offered incremental prognostic information for predicting adverse cardiac outcome, and hence for better patient risk stratification, over those provided by traditional clinical risk predictors. This article reviews the available evidence to support the translation of the current techniques and technologies into a useful decision-making tool in real-world clinical practice.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
385-400Subventions
Organisme : Turun Yliopistollinen Keskussairaala
Organisme : Academy of Finland
Organisme : Finnish Foundation for Cardiovascular Research
Organisme : Hospital District of Southwest Finland
Informations de copyright
© 2021 The Authors. Clinical Physiology and Functional Imaging published by John Wiley & Sons Ltd on behalf of Scandinavian Society of Clinical Physiology and Nuclear Medicine.
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