Towards point-of-care diagnosis of Alzheimer's disease: Multi-analyte based portable chemiresistive platform for simultaneous detection of β-amyloid (1-40) and (1-42) in plasma.

Alzheimer’s Electronic readout Mobile interfacing Point-of-care Polypyrrole-chemiresistive Portable sensors

Journal

Biosensors & bioelectronics
ISSN: 1873-4235
Titre abrégé: Biosens Bioelectron
Pays: England
ID NLM: 9001289

Informations de publication

Date de publication:
04 May 2021
Historique:
received: 07 02 2021
revised: 11 04 2021
accepted: 28 04 2021
pubmed: 11 5 2021
medline: 11 5 2021
entrez: 10 5 2021
Statut: aheadofprint

Résumé

Label-free simultaneous detection of Alzheimer's disease (AD) specific biomarkers Aβ40 and Aβ42 peptides on a single platform using polypyrrole nanoparticle-based chemiresistive biosensors is reported here. The proposed interdigitated-microelectrode based inexpensive multisensor-platform can concurrently detect Aβ40 and Aβ42 in spiked-plasma in the range of 10

Identifiants

pubmed: 33971525
pii: S0956-5663(21)00331-6
doi: 10.1016/j.bios.2021.113294
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

113294

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Patta Supraja (P)

Department of Electrical Engineering, Indian Institute of Technology Hyderabad, 502285, India. Electronic address: ee17resch01006@iith.ac.in.

Suryasnata Tripathy (S)

Department of Electrical Engineering, Indian Institute of Technology Hyderabad, 502285, India. Electronic address: suryasnata.tripathy@gmail.com.

Ranjana Singh (R)

Department of Electrical Engineering, Indian Institute of Technology Hyderabad, 502285, India. Electronic address: ch18pdf04@iith.ac.in.

Vikrant Singh (V)

School of Medicine, University of California Davis, USA. Electronic address: vssingh@ucdavis.edu.

Gajendranath Chaudhury (G)

Department of Electrical Engineering, Indian Institute of Technology Hyderabad, 502285, India. Electronic address: gajendranath@ee.iith.ac.in.

Shiv Govind Singh (SG)

Department of Electrical Engineering, Indian Institute of Technology Hyderabad, 502285, India. Electronic address: sgsingh@ee.iith.ac.in.

Classifications MeSH