Socialization During the COVID-19 Pandemic: The Role of Social and Scientific Networks During Social Distancing.
COVID-19
Pandemic
Scientific network
Social distancing
Social network
Socialization
Journal
Advances in experimental medicine and biology
ISSN: 0065-2598
Titre abrégé: Adv Exp Med Biol
Pays: United States
ID NLM: 0121103
Informations de publication
Date de publication:
2021
2021
Historique:
entrez:
11
5
2021
pubmed:
12
5
2021
medline:
13
5
2021
Statut:
ppublish
Résumé
In the COVID-19 era, while we are encouraged to be physically far away from each other, social and scientific networking is needed more than ever. The dire consequences of social distancing can be diminished by social networking. Social media, a quintessential component of social networking, facilitates the dissemination of reliable information and fighting against misinformation by health authorities. Distance learning, telemedicine, and telehealth are among the most prominent applications of networking during this pandemic. Additionally, the COVID-19 pandemic highlights the importance of collaborative scientific efforts. In this chapter, we summarize the advantages of harnessing both social and scientific networking in minimizing the harms of this pandemic. We also discuss the extra collaborative measures we can take in our fight against COVID-19, particularly in the scientific field.
Identifiants
pubmed: 33973219
doi: 10.1007/978-3-030-63761-3_51
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
911-921Références
Ahanchian H, Moazzen N, Faroughi MSD, Khalighi N, Khoshkhui M, Aelami MH, Haghi NSM, Rezaei N (2020) COVID-19 in a child with primary specific antibody deficiency
Aimone F (2010) The 1918 influenza epidemic in New York City: a review of the public health response. Public Health Rep 125(Suppl 3):71–79. https://doi.org/10.1177/00333549101250S310
doi: 10.1177/00333549101250S310
pubmed: 20568569
pmcid: 2862336
Babaha F, Rezaei N (2020) Primary immunodeficiency diseases in COVID-19 pandemic: a predisposing or protective factor? Am J Med Sci. https://doi.org/10.1016/j.amjms.2020.07.027
Bahrami A, Vafapour M, Moazzami B, Rezaei N (2020) Hyperinflammatory shock related to COVID-19 in a patient presenting with multisystem inflammatory syndrome in children: first case from Iran. J Paediatr Child Health. https://doi.org/10.1111/jpc.15048
Basiri A, Heidari A, Nadi MF, Fallahy MTP, Nezamabadi SS, Sedighi M, Saghazadeh A, Rezaei N (2020a) Microfluidic devices for detection of RNA viruses. Rev Med Virol n/a(n/a):e2154. https://doi.org/10.1002/rmv.2154
doi: 10.1002/rmv.2154
Basiri A, Pazhouhnia Z, Beheshtizadeh N, Hoseinpour M, Saghazadeh A, Rezaei N (2020b) Regenerative medicine in COVID-19 treatment: real opportunities and range of promises. Stem Cell Rev Rep:1–13. https://doi.org/10.1007/s12015-020-09994-5
Boehm K, Ziewers S, Brandt MP, Sparwasser P, Haack M, Willems F, Thomas A, Dotzauer R, Hofner T, Tsaur I, Haferkamp A, Borgmann H (2020) Telemedicine online visits in urology during the COVID-19 pandemic-potential, risk factors, and Patients’ perspective. Eur Urol. https://doi.org/10.1016/j.eururo.2020.04.055
Breugelmans JG, Roberge G, Tippett C, Durning M, Struck DB, Makanga MM (2018) Scientific impact increases when researchers publish in open access and international collaboration: a bibliometric analysis on poverty-related disease papers. PLoS One 13(9):e0203156. https://doi.org/10.1371/journal.pone.0203156
doi: 10.1371/journal.pone.0203156
pubmed: 30231044
pmcid: 6145557
Busvine D (2020) Science platform ResearchGate launches COVID-19 community. Reuters. https://www.reuters.com/article/us-health-coronavirus-tech-researchgate/science-platform-researchgate-launches-covid-19-community-idUSKBN21O1QD . Accessed 20 April 2020
Canales K (2020) Photos show the precautions US cities took to ‘flatten the curve’ during the 1918 Spanish Flu pandemic Business Insider. https://www.businessinsider.fr/us/spanish-flu-pandemic-1918-precautions-us-cities-2020-4
Chinchilla-Rodriguez Z, Sugimoto CR, Lariviere V (2019) Follow the leader: on the relationship between leadership and scholarly impact in international collaborations. PLoS One 14(6):e0218309. https://doi.org/10.1371/journal.pone.0218309
doi: 10.1371/journal.pone.0218309
pubmed: 31220123
pmcid: 6586445
Cosic K, Popovic S, Sarlija M, Kesedzic I (2020) Impact of human disasters and COVID-19 pandemic on mental health: potential of digital psychiatry. Psychiatr Danub 32(1):25–31. https://doi.org/10.24869/psyd.2020.25
doi: 10.24869/psyd.2020.25
pubmed: 32303026
Coursera (2020) Coursera together: free online learning during COVID-19. https://blog.coursera.org/coursera-together-free-online-learning-during-covid-19/ . Accessed 4 May 2020
Cuan-Baltazar JY, Munoz-Perez MJ, Robledo-Vega C, Perez-Zepeda MF, Soto-Vega E (2020) Misinformation of COVID-19 on the internet: Infodemiology study. JMIR Public Health Surveill 6(2):e18444. https://doi.org/10.2196/18444
doi: 10.2196/18444
pubmed: 32250960
pmcid: 7147328
Darbeheshti F, Rezaei N (2020) Genetic predisposition models to COVID-19 infection. Med Hypotheses 142:109818. https://doi.org/10.1016/j.mehy.2020.109818
doi: 10.1016/j.mehy.2020.109818
pubmed: 32416414
pmcid: 7202332
edX (2020) edX’s Response to COVID-19. https://www.edx.org/covid-19 . Accessed 4 May 2020
Facebook (2020) Coronavirus (COVID-19) information hub for media. https://www.facebook.com/facebookmedia/solutions/coronavirus-resources . Accessed 4 May 2020
Fathi N, Rezaei N (2020) Lymphopenia in COVID-19: therapeutic opportunities. Cell Biol Int 44(9):1792–1797. https://doi.org/10.1002/cbin.11403
doi: 10.1002/cbin.11403
pubmed: 32458561
pmcid: 32458561
Galea S, Merchant RM, Lurie N (2020) The mental health consequences of COVID-19 and physical distancing: the need for prevention and early intervention. JAMA Intern Med. https://doi.org/10.1001/jamainternmed.2020.1562
Government-of-india (2020) Aarogya Setu mobile app. https://www.mygov.in/aarogya-setu-app/ . Accessed 17 May 2020
Hakim AA, Kellish AS, Atabek U, Spitz FR, Hong YK (2020) Implications for the use of telehealth in surgical patients during the COVID-19 pandemic. Am J Surg. https://doi.org/10.1016/j.amjsurg.2020.04.026
Hawryluck L, Gold WL, Robinson S, Pogorski S, Galea S, Styra R (2004) SARS control and psychological effects of quarantine, Toronto, Canada. Emerg Infect Dis 10(7):1206–1212. https://doi.org/10.3201/eid1007.030703
doi: 10.3201/eid1007.030703
pubmed: 15324539
pmcid: 3323345
Hollander JE, Carr BG (2020) Virtually perfect? Telemedicine for Covid-19. N Engl J Med 382(18):1679–1681. https://doi.org/10.1056/NEJMp2003539
doi: 10.1056/NEJMp2003539
pubmed: 32160451
Holmes EA, O’Connor RC, Perry VH, Tracey I, Wessely S, Arseneault L, Ballard C, Christensen H, Cohen Silver R, Everall I, Ford T, John A, Kabir T, King K, Madan I, Michie S, Przybylski AK, Shafran R, Sweeney A, Worthman CM, Yardley L, Cowan K, Cope C, Hotopf M, Bullmore E (2020) Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science. Lancet Psychiatry. https://doi.org/10.1016/S2215-0366(20)30168-1
Jabbari P, Jabbari F, Ebrahimi S, Rezaei N (2020) COVID-19: a chimera of two pandemics. Disaster Med Public Health Prep:1–2. https://doi.org/10.1017/dmp.2020.223
Jabbari P, Rezaei N (2020) With risk of reinfection, is COVID-19 here to stay? Disaster Med Pub Heal Prep 1. https://doi.org/10.1017/dmp.2020.274
Jahanshahlu L, Rezaei N (2020a) Central nervous system involvement in COVID-19. Arch Med Res. https://doi.org/10.1016/j.arcmed.2020.05.016
Jahanshahlu L, Rezaei N (2020b) Monoclonal antibody as a potential anti-COVID-19. Biomed Pharmacoth Biomed Pharma 129:110337. https://doi.org/10.1016/j.biopha.2020.110337
doi: 10.1016/j.biopha.2020.110337
Jeong H, Yim HW, Song YJ, Ki M, Min JA, Cho J, Chae JH (2016) Mental health status of people isolated due to Middle East respiratory syndrome. Epidemiol Health 38:e2016048. https://doi.org/10.4178/epih.e2016048
doi: 10.4178/epih.e2016048
pubmed: 28196409
pmcid: 5177805
Jones D, Neal RD, Duffy SRG, Scott SE, Whitaker KL, Brain K Impact of the COVID-19 pandemic on the symptomatic diagnosis of cancer: the view from primary care. Lancet Oncol. https://doi.org/10.1016/S1470-2045(20)30242-4
Kafieh R, Arian R, Saeedizadeh N, Minaee S, Yadav SK, Vaezi A, Rezaei N, Javanmard SH (2020) COVID-19 in Iran: a deeper look into the future. medRxiv
Lager S (2020) Udacity’s contribution to the COVID-19 crisis: one free month access to nanodegree programs udacity. https://blog.udacity.com/2020/03/one-month-free-on-nanodegrees.html . Accessed 17 May 2020
Lai J, Ma S, Wang Y, Cai Z, Hu J, Wei N, Wu J, Du H, Chen T, Li R, Tan H, Kang L, Yao L, Huang M, Wang H, Wang G, Liu Z, Hu S (2020) Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019. JAMA Netw Open 3(3):e203976. https://doi.org/10.1001/jamanetworkopen.2020.3976
doi: 10.1001/jamanetworkopen.2020.3976
pubmed: 32202646
pmcid: 7090843
Latifi R, Doarn CR (2020) Perspective on COVID-19: finally, telemedicine at center stage. Telemed e-Heal. https://doi.org/10.1089/tmj.2020.0132
Liang ZC, Ooi SBS, Wang W (2020) Pandemics and their impact on medical training: lessons from Singapore. Acad Med. https://doi.org/10.1097/ACM.0000000000003441
Limaye RJ, Sauer M, Ali J, Bernstein J, Wahl B, Barnhill A, Labrique A Building trust while influencing online COVID-19 content in the social media world. Lancet Dig Heal. https://doi.org/10.1016/S2589-7500(20)30084-4
Lotfi M, Hamblin MR, Rezaei N (2020) COVID-19: transmission, prevention, and potential therapeutic opportunities. Clinica Chimica Acta Int J Clin Chem 508:254–266. https://doi.org/10.1016/j.cca.2020.05.044
doi: 10.1016/j.cca.2020.05.044
Lotfi M, Rezaei N (2020) SARS-CoV-2: a comprehensive review from pathogenicity of the virus to clinical consequences. J Med Virol. https://doi.org/10.1002/jmv.26123
Mahase E (2020) Covid-19: UK starts social distancing after new model points to 260 000 potential deaths. BMJ 368:m1089. https://doi.org/10.1136/bmj.m1089
doi: 10.1136/bmj.m1089
pubmed: 32184205
Mansourabadi AH, Sadeghalvad M, Mohammadi-Motlagh HR, Rezaei N (2020) The immune system as a target for therapy of SARS-CoV-2: a systematic review of the current immunotherapies for COVID-19. Life Sci 258:118185. https://doi.org/10.1016/j.lfs.2020.118185
doi: 10.1016/j.lfs.2020.118185
pubmed: 32750438
pmcid: 7395832
Merchant RM, Lurie N (2020) Social media and emergency preparedness in response to novel coronavirus. JAMA. https://doi.org/10.1001/jama.2020.4469
Mian A, Khan S (2020) Medical education during pandemics: a UK perspective. BMC Med 18(1):100. https://doi.org/10.1186/s12916-020-01577-y
doi: 10.1186/s12916-020-01577-y
pubmed: 32268900
pmcid: 7141929
Moazzami B, Razavi-Khorasani N, Dooghaie Moghadam A, Farokhi E, Rezaei N (2020) COVID-19 and telemedicine: immediate action required for maintaining healthcare providers Well-being. J Clin Virol Off Publ Pan Am Soc Clin Virol 126:104345. https://doi.org/10.1016/j.jcv.2020.104345
doi: 10.1016/j.jcv.2020.104345
Mohamed K, Rodríguez-Román E, Rahmani F, Zhang H, Ivanovska M, Makka SA, Joya M, Makuku R, Islam MS, Radwan N, Rahmah L, Goda R, Abarikwu SO, Shaw M, Zoghi S, Irtsyan S, Ling I, Cseprekal O, Faten A-B, Hazar E, Tbalvandany CS, Grancini G, Rezaei N (2020a) Borderless collaboration is needed for COVID-19; a disease that knows no borders. Infect Control Hosp Epidemiol:1–7. https://doi.org/10.1017/ice.2020.162
Mohamed K, Yazdanpanah N, Saghazadeh A, Rezaei N (2020b) Computational drug discovery and repurposing for the treatment of Covid-19: a systematic review. Available at SSRN 3583748
Momtazmanesh S, Ochs HD, Uddin LQ, Perc M, Routes JM, Vieira DN, Al-Herz W, Baris S, Prando C, Rosivall L, Abdul Latiff AH, Ulrichs T, Roudenok V, Aldave Becerra JC, Salunke DB, Goudouris E, Condino-Neto A, Stashchak A, Kryvenko O, Stashchak M, Bondarenko A, Rezaei N (2020) All together to fight novel coronavirus disease (COVID-19). Am J Trop Med Hyg. https://doi.org/10.4269/ajtmh.20-0281
Moradian N, Ochs HD, Sedikies C, Hamblin MR, Camargo CA, Martinez JA, Biamonte JD, Abdollahi M, Torres PJ, Nieto JJ, Ogino S, Seymour JF, Abraham A, Cauda V, Gupta S, Ramakrishna S, Sellke FW, Sorooshian A, Wallace Hayes A, Martinez-Urbistondo M, Gupta M, Azadbakht L, Esmaillzadeh A, Kelishadi R, Esteghamati A, Emam-Djomeh Z, Majdzadeh R, Palit P, Badali H, Rao I, Saboury AA, Jagan Mohan Rao L, Ahmadieh H, Montazeri A, Fadini GP, Pauly D, Thomas S, Moosavi-Movahed AA, Aghamohammadi A, Behmanesh M, Rahimi-Movaghar V, Ghavami S, Mehran R, Uddin LQ, Von Herrath M, Mobasher B, Rezaei N (2020) The urgent need for integrated science to fight COVID-19 pandemic and beyond. J Transl Med 18(1):205. https://doi.org/10.1186/s12967-020-02364-2
doi: 10.1186/s12967-020-02364-2
pubmed: 32430070
pmcid: 7236639
Nasab MG, Saghazadeh A, Rezaei N (2020) SARS-CoV-2-a tough opponent for the immune system. Arch Med Res. https://doi.org/10.1016/j.arcmed.2020.05.020
Nature (2020) Show evidence that apps for COVID-19 contact-tracing are secure and effective. Nature 580(7805):563. https://doi.org/10.1038/d41586-020-01264-1
doi: 10.1038/d41586-020-01264-1
Ohannessian R, Duong TA, Odone A (2020) Global telemedicine implementation and integration within health systems to fight the COVID-19 pandemic: a call to action. JMIR Public Health Surveill 6(2):e18810. https://doi.org/10.2196/18810
doi: 10.2196/18810
pubmed: 32238336
pmcid: 7124951
Oxford (2020) Social networking. Oxford University Press. https://www.oxfordlearnersdictionaries.com/definition/english/social-networking . Accessed 4 May 2020
Panahi S, Watson J, Partridge H (2016) Social media and physicians: exploring the benefits and challenges. Health Informatics J 22(2):99–112. https://doi.org/10.1177/1460458214540907
doi: 10.1177/1460458214540907
pubmed: 25038200
Pashaei M, Rezaei N (2020) Immunotherapy for SARS-CoV-2: potential opportunities. Expert Opin Biol Ther:1–5. https://doi.org/10.1080/14712598.2020.1807933
Pourahmad R, Moazzami B, Rezaei N (2020) Efficacy of plasmapheresis and immunoglobulin replacement therapy (IVIG) on patients with COVID-19. SN Comprehen Clin Med:1–5
Public (2020) Public statement for collaboration on COVID-19 vaccine development. https://www.who.int/news-room/detail/13-04-2020-public-statement-for-collaboration-on-covid-19-vaccine-development . Accessed 4 May 2020
Qiu J, Shen B, Zhao M, Wang Z, Xie B, Xu Y (2020) A nationwide survey of psychological distress among Chinese people in the COVID-19 epidemic: implications and policy recommendations. Gen Psychiatr 33(2):e100213. https://doi.org/10.1136/gpsych-2020-100213
doi: 10.1136/gpsych-2020-100213
pubmed: 32215365
pmcid: 7061893
Rabiee N, Rabiee M, Bagherzadeh M, Rezaei N (2020) COVID-19 and picotechnology: potential opportunities. Med Hypotheses 144:109917. https://doi.org/10.1016/j.mehy.2020.109917
doi: 10.1016/j.mehy.2020.109917
pubmed: 32505072
pmcid: 7263242
Rahmani F (2020) Advisory board, junior ambassadors, and interest groups respond to COVID19. https://usern.tums.ac.ir/News/New?title=Advisory%20Board,%20Junior%20Ambassadors,%20and%20Interest%20Groups%20Respond%20to%20COVID19 . Accessed 4 May 2020
ResearchGate (2020) Combating COVID-19. ResearchGate GMBH. https://www.researchgate.net/COVID-19 . Accessed 4 May 2020
Rezaei N (2016) Universal scientific education and research network (USERN):a new horizon for science. Acta Med Iran 54(1):1–3
pubmed: 26853283
Rezaei N (2017) Universal scientific education and research network (USERN): to make the knowledge without Borders. Acta Med Iran 55(1):1–5
pubmed: 28188937
Rezaei N (2018) Universal scientific education and research network (USERN): twinkling stars unite to make the world glow. Acta Med Iran 56(1):1–3
pubmed: 29436788
Rezaei N (2020a) COVID-19 affects healthy pediatricians more than pediatric patients. Infect Cont Hosp Epidemiol 1. https://doi.org/10.1017/ice.2020.139
Rezaei N (2020b) COVID-19 and medical biotechnology. Avicenna J Med Biotechnol 12(3):139
pubmed: 32695275
pmcid: 32695275
Richards D, Vigano N (2013) Online counseling: a narrative and critical review of the literature. J Clin Psychol 69(9):994–1011. https://doi.org/10.1002/jclp.21974
doi: 10.1002/jclp.21974
pubmed: 23630010
Rokni M, Hamblin MR, Rezaei N (2020) Cytokines and COVID-19: friends or foes? Hum Vaccin Immunother:1–3
Rosenbaum L (2020) The untold toll — the Pandemic’s effects on patients without Covid-19. N Engl J Med. https://doi.org/10.1056/NEJMms2009984
Rzymski P, Nowicki M, Mullin GE, Abraham A, Rodríguez-Román E, Petzold MB, Bendau A, Sahu KK, Ather A, Naviaux A-F (2020) Quantity does not equal quality: scientific principles cannot be sacrificed. Int Immunopharmacol 86:106711
doi: 10.1016/j.intimp.2020.106711
Saghazadeh A, Rezaei N (2020a) Immune-epidemiological parameters of the novel coronavirus – a perspective. Expert Rev Clin Immunol
Saghazadeh A, Rezaei N (2020b) Towards treatment planning of COVID-19: rationale and hypothesis for the use of multiple immunosuppressive agents: anti-antibodies, immunoglobulins, and corticosteroids. Int Immunopharmacol 84:106560. https://doi.org/10.1016/j.intimp.2020.106560
doi: 10.1016/j.intimp.2020.106560
pubmed: 32413736
pmcid: 7205724
Sahu KK, Siddiqui AD, Rezaei N, Cerny J (2020) Challenges for management of immune thrombocytopenia during COVID-19 pandemic. J Med Virol. https://doi.org/10.1002/jmv.26251
Saleem SM, Pasquale LR, Sidoti PA, Tsai JC (2020) Virtual ophthalmology: telemedicine in a Covid-19 era. Am J Ophthalmol. https://doi.org/10.1016/j.ajo.2020.04.029
Saleki K, Banazadeh M, Saghazadeh A, Rezaei N (2020) The involvement of the central nervous system in patients with COVID-19. Rev Neurosci 31(4):453–456. https://doi.org/10.1515/revneuro-2020-0026
doi: 10.1515/revneuro-2020-0026
pubmed: 32463395
Shamshirian D, Rezaei N (2020) Cardiovascular diseases burden in COVID-19: systematic review and meta-analysis
Sharifkashani S, Bafrani MA, Khaboushan AS, Pirzadeh M, Kheirandish A, Yavarpour Bali H, Hessami A, Saghazadeh A, Rezaei N (2020) Angiotensin-converting enzyme 2 (ACE2) receptor and SARS-CoV-2: potential therapeutic targeting. Eur J Pharmacol 884:173455. https://doi.org/10.1016/j.ejphar.2020.173455
doi: 10.1016/j.ejphar.2020.173455
pubmed: 32745604
pmcid: 7834210
Statista (2019) Number of social network users worldwide from 2010 to 2023 Statista website. https://www.statista.com/statistics/278414/number-of-worldwide-social-network-users/ . Accessed 30 April 2020
Statt N (2020) Major tech platforms say they’re ‘jointly combating fraud and misinformation’ about COVID-19. The Verge. https://www.theverge.com/2020/3/16/21182726/coronavirus-covid-19-facebook-google-twitter-youtube-joint-effort-misinformation-fraud . Accessed 4 May 2020
Twitter (2020) Coronavirus: staying safe and informed on Twitter. https://blog.twitter.com/en_us/topics/company/2020/covid-19.html . Accessed 4 May 2020
Venkatesh A, Edirappuli S (2020) Social distancing in covid-19: what are the mental health implications? BMJ 369:m1379. https://doi.org/10.1136/bmj.m1379
doi: 10.1136/bmj.m1379
pubmed: 32253182
Walsh K, Sandars J, Nordquist J (2018) Technology-enhanced learning for healthcare professionals: an essential response to infectious disease pandemics. BMJ Simulat Technol Enhan Learn 4(1):1. https://doi.org/10.1136/bmjstel-2017-000236
doi: 10.1136/bmjstel-2017-000236
Wang C, Horby PW, Hayden FG, Gao GF (2020) A novel coronavirus outbreak of global health concern. Lancet 395(10223):470–473. https://doi.org/10.1016/S0140-6736(20)30185-9
doi: 10.1016/S0140-6736(20)30185-9
pubmed: 31986257
pmcid: 7135038
WHO (2020) WHO Director-General’s opening remarks at the media briefing on COVID-19 https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19%2D%2D-18-march-2020
World_Bank (2020) Remote learning, distance education and online learning during the COVID19 pandemic: a resource list by the World Bank’s Edtech Team (English). World Bank Group, Washington, DC
doi: 10.1596/33499
Yazdanpanah F, Hamblin MR, Rezaei N (2020a) The immune system and COVID-19: friend or foe? Life Sci 256:117900. https://doi.org/10.1016/j.lfs.2020.117900
doi: 10.1016/j.lfs.2020.117900
pubmed: 32502542
pmcid: 7266583
Yazdanpanah N, Saghazadeh A, Rezaei N (2020b) Anosmia: a missing link in the neuroimmunology of coronavirus disease 2019 (COVID-19). Rev Neurosci. https://doi.org/10.1515/revneuro-2020-0039
Yousefzadegan S, Rezaei N (2020) Death due to COVID-19 in three brothers. Am J Trop Med Hyg
Zarocostas J (2020) How to fight an infodemic. Lancet 395(10225):676. https://doi.org/10.1016/S0140-6736(20)30461-X
doi: 10.1016/S0140-6736(20)30461-X
pubmed: 32113495
pmcid: 7133615
Zastrow M (2020) South Korea is reporting intimate details of COVID-19 cases: has it helped? Nature. https://doi.org/10.1038/d41586-020-00740-y