A clinical comparison of pure knitted silk and a complex synthetic skin substitute for the treatment of partial thickness burns.
Dressilk
POSAS
Suprathel
partial thickness burns
wound healing
Journal
International wound journal
ISSN: 1742-481X
Titre abrégé: Int Wound J
Pays: England
ID NLM: 101230907
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
revised:
24
04
2021
received:
15
02
2021
accepted:
27
04
2021
pubmed:
12
5
2021
medline:
22
12
2021
entrez:
11
5
2021
Statut:
ppublish
Résumé
Currently, many dressings are commercially available for the treatment of burn wounds. Some of these wound dressings remain on the wound, prevent painful dressing changes, and reduce tissue scarring. Nevertheless, still a wound dressing that is cost-effective, produces good wound healing properties, and has a high patient satisfaction is needed. Standard care of superficial burn wounds differs between burn centres. This study aimed to determine a dressing with easy appliance, accurate pain control, favourable outcome, and cost-effectiveness. Therefore, we compared the widely used but expensive Suprathel with the rather new but much cheaper Dressilk in the clinical setting. In a prospective clinical study, the healing of partial thickness burn wounds after simultaneous treatment with Suprathel and Dressilk was examined in 20 patients intra-individually. During wound healing, pain, infection, exudation, and bleeding were evaluated. A subjective scar evaluation was performed using the Patient and Observer Scar Scale. Both dressings were easy to apply, remained on the wound in place, and were gradually cut back as reepithelisation proceeded and showed similar times to wound closure. Dressing changes were not necessary, and neither infections nor bleeding was detected. Overall exudation and pain were highest in the beginning but declined during the wound-healing phase without significant differences. In the follow-up scar evaluation after 12 months, patients reported overall high satisfaction. Overall, the modern dressings Suprathel and Dressilk (solely made out of pure silk) led to safe wound healing without infection and rapidly reduced pain. There was no need for dressing changes, and they had similar clinical outcomes in scar evaluation. Therefore, both dressings seem to be ideal for the treatment of superficial burns. Because acquisition costs remain one of the main factors in the treatment of burns, Dressilk, which is ~20 times cheaper than Suprathel, remains a good option for the treatment of partial thickness burns.
Identifiants
pubmed: 33973387
doi: 10.1111/iwj.13613
pmc: PMC8684860
doi:
Substances chimiques
Silk
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
178-187Subventions
Organisme : Prevor (company)
Informations de copyright
© 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.
Références
Burns. 2016 Aug;42(5):e86-e92
pubmed: 27233678
Ann Plast Surg. 2008 Feb;60(2):181-5
pubmed: 18216512
Plast Reconstr Surg. 2004 Jun;113(7):1960-5; discussion 1966-7
pubmed: 15253184
Arch Surg. 1995 Sep;130(9):999-1006
pubmed: 7661688
Burns. 2016 Jun;42(4):763-8
pubmed: 26948956
Burns. 1994 Apr;20(2):180-1
pubmed: 8198728
Adv Drug Deliv Rev. 2020 Jan 1;153:28-53
pubmed: 31678360
J Burn Care Res. 2013 Mar-Apr;34(2):e60-79
pubmed: 23446645
J Burn Care Res. 2018 Feb 20;39(2):261-267
pubmed: 28557869
Burns. 2016 Mar;42(2):345-55
pubmed: 25720659
Nature. 1955 Apr 30;175(4461):760-3
pubmed: 14370212
Burns. 2015 Dec;41(8):1811-1815
pubmed: 26188896
Burns. 2001 Aug;27(5):534-44
pubmed: 11451612
Burns. 2013 Feb;39(1):136-41
pubmed: 22698841
Nanomedicine. 2015 Apr;11(3):681-91
pubmed: 25555351
Int J Biol Macromol. 2016 Apr;85:29-39
pubmed: 26718866
Integr Biol (Camb). 2015 Jan;7(1):53-63
pubmed: 25372050
Burns. 2015 Dec;41(8):1642-1652
pubmed: 26452308
Int J Low Extrem Wounds. 2007 Jun;6(2):82-97
pubmed: 17558006
Int Wound J. 2022 Jan;19(1):178-187
pubmed: 33973387
Indian J Plast Surg. 2010 Sep;43(Suppl):S101-13
pubmed: 21321643
Wounds. 2014 Mar;26(3):77-82
pubmed: 25860332
Arch Dermatol Res. 2013 Sep;305(7):585-94
pubmed: 23748948
Burns. 2018 Mar;44(2):305-317
pubmed: 28865837
Qual Life Res. 2012 Feb;21(1):13-23
pubmed: 21598065
Burns. 2015 Aug;41(5):946-55
pubmed: 25687836
Langenbecks Arch Klin Chir Ver Dtsch Z Chir. 1953;274(6-7):510-33
pubmed: 13085832
Can J Surg. 2015 Aug;58(4):245-9
pubmed: 26022156
Mater Sci Eng C Mater Biol Appl. 2014 Oct;43:11-20
pubmed: 25175182
Macromol Biosci. 2010 Sep 9;10(9):998-1007
pubmed: 20602494
Nanoscale. 2011 Mar;3(3):870-6
pubmed: 21212901
Ann Plast Surg. 2008 Mar;60(3):333-7
pubmed: 18443516
Burns. 2019 Sep;45(6):1311-1324
pubmed: 31327551
Plast Reconstr Surg. 2007 Feb;119(2):487-94
pubmed: 17230080
Burns. 2017 May;43(3):539-548
pubmed: 28043735
Burns. 2015 Dec;41(8):1855-1861
pubmed: 26456911
J Pharm Sci. 2008 Aug;97(8):2892-923
pubmed: 17963217
Int J Biol Macromol. 2020 Dec 1;164:4613-4627
pubmed: 32814099
Arch Plast Surg. 2014 Mar;41(2):111-5
pubmed: 24665417
Lasers Surg Med. 2017 Aug;49(6):563-569
pubmed: 28220505
J Burn Care Rehabil. 2000 May-Jun;21(3):205-12
pubmed: 10850901
Burns. 2007 Mar;33(2):221-9
pubmed: 17084030
Adv Drug Deliv Rev. 2018 Jan 1;123:3-17
pubmed: 28941987
J Burn Care Res. 2018 Jun 13;39(4):516-526
pubmed: 29596600
Adv Funct Mater. 2013 Feb 18;23(7):854-861
pubmed: 23483738
Ostomy Wound Manage. 2002 Nov;48(11):28-40
pubmed: 12426450
Medicine (Baltimore). 2017 Mar;96(9):e6168
pubmed: 28248871