Alexithymia and somatization in agenesis of the corpus callosum.
alexithymia
connectivity
corpus callosum
emotion
somatic complaints
Journal
Social cognitive and affective neuroscience
ISSN: 1749-5024
Titre abrégé: Soc Cogn Affect Neurosci
Pays: England
ID NLM: 101288795
Informations de publication
Date de publication:
30 09 2021
30 09 2021
Historique:
received:
12
08
2020
revised:
02
03
2021
accepted:
11
05
2021
pubmed:
12
5
2021
medline:
25
2
2023
entrez:
11
5
2021
Statut:
ppublish
Résumé
Deficient communication between the cerebral hemispheres is one of several prevailing neurobiological explanations for alexithymia and has been strongly supported by research on patients with commissurotomy. We examined self-reported symptoms of alexithymia in adults with agenesis of the corpus callosum (AgCC), a condition characterized by more subtle reductions in interhemispheric transfer than in commissurotomy. Sixteen adults with AgCC and full-scale intelligence quotient >80 were compared with 15 neurotypical controls group-matched for age and intelligence score. The AgCC group endorsed greater difficulty identifying and describing feelings and more vague physical symptoms than controls but similar levels of emotional experience and emotional coping. This finding of impaired emotional interpretation with intact emotional experience is consistent with findings in callosotomy patients, implicating the critical role of the corpus callosum in cognitive dimensions of emotion processing. Further study of alexithymia in AgCC using task-based measures may help clarify the nature of this relationship.
Identifiants
pubmed: 33973635
pii: 6273469
doi: 10.1093/scan/nsab056
pmc: PMC8483281
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1071-1078Subventions
Organisme : Eunice Kennedy Shriver National Institute of Child Health and Human Development
ID : R15 HD33118-01A1
Informations de copyright
© The Author(s) 2021. Published by Oxford University Press.
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