Natural deep eutectic systems, an emerging class of cryoprotectant agents.
Biomaterials
Cryobiology
Cryopreservation
Freeze-thawing
Natural deep eutectic systems
Natural metabolites
Journal
Cryobiology
ISSN: 1090-2392
Titre abrégé: Cryobiology
Pays: Netherlands
ID NLM: 0006252
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
received:
15
02
2021
revised:
07
04
2021
accepted:
05
05
2021
pubmed:
12
5
2021
medline:
23
9
2021
entrez:
11
5
2021
Statut:
ppublish
Résumé
This work aimed at evaluating the potential of using natural deep eutectic systems (NADES) as cryoprotectant agents (CPAs). Several combinations between natural primary metabolites that have been identified in animals that live in extreme cold climates were prepared. All systems showed very little cytoxicity towards L929 cells at concentrations high as 1-2 M. Moreover, this cell line was highly tolerant to 10% (w/v) of NADES when compared to Me
Identifiants
pubmed: 33974836
pii: S0011-2240(21)00082-1
doi: 10.1016/j.cryobiol.2021.05.002
pmc: PMC8355309
pii:
doi:
Substances chimiques
Cryoprotective Agents
0
Solvents
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
95-104Informations de copyright
Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.
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