Transgenerational fitness effects of lifespan extension by dietary restriction in


Journal

Proceedings. Biological sciences
ISSN: 1471-2954
Titre abrégé: Proc Biol Sci
Pays: England
ID NLM: 101245157

Informations de publication

Date de publication:
12 05 2021
Historique:
entrez: 12 5 2021
pubmed: 13 5 2021
medline: 21 5 2021
Statut: ppublish

Résumé

Dietary restriction (DR) increases lifespan in a broad variety of organisms and improves health in humans. However, long-term transgenerational consequences of dietary interventions are poorly understood. Here, we investigated the effect of DR by temporary fasting (TF) on mortality risk, age-specific reproduction and fitness across three generations of descendants in

Identifiants

pubmed: 33975472
doi: 10.1098/rspb.2021.0701
pmc: PMC8113902
doi:

Substances chimiques

Caenorhabditis elegans Proteins 0

Banques de données

Dryad
['10.5061/dryad.fn2z34tt9']
figshare
['10.6084/m9.figshare.c.5410688']

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

20210701

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R017387/1
Pays : United Kingdom

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Auteurs

Edward R Ivimey-Cook (ER)

School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TU, UK.

Kris Sales (K)

School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TU, UK.

Hanne Carlsson (H)

School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TU, UK.

Simone Immler (S)

School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TU, UK.

Tracey Chapman (T)

School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TU, UK.

Alexei A Maklakov (AA)

School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TU, UK.

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Classifications MeSH