Protracted Hiccups Induced by Aripiprazole and Regressed after Administration of Gabapentin.
Journal
Case reports in psychiatry
ISSN: 2090-682X
Titre abrégé: Case Rep Psychiatry
Pays: United States
ID NLM: 101583308
Informations de publication
Date de publication:
2021
2021
Historique:
received:
19
02
2021
revised:
15
04
2021
accepted:
16
04
2021
entrez:
12
5
2021
pubmed:
13
5
2021
medline:
13
5
2021
Statut:
epublish
Résumé
Hiccups are sudden, repeated, and involuntary contractions of the diaphragm muscle (myoclonic contraction). It involves a reflex arc that, once activated, causes a strong contraction of the diaphragm immediately followed by the closure of the glottis translating into the classic "hic" sound. Hiccups can be short, persistent, and intractable depending on the duration. The most disabling hiccups often represent the epiphenomenon of a medical condition such as gastrointestinal and cardiovascular disorders; central nervous system (CNS) abnormalities; ear, nose, and throat (ENT) conditions or pneumological problems; metabolic/endocrine disorders; infections; and psychogenic disorders. Some drugs, such as aripiprazole, a second-generation antipsychotic, can induce the onset of variable hiccups. We describe herein the cases of three hospitalized patients who developed insistent hiccups after taking aripiprazole and who positively responded to low doses of gabapentin. It is probable that aripiprazole, prescribed at a low dosage (<7.5 mg/day), would act as a dopamine agonist by stimulating D
Identifiants
pubmed: 33976948
doi: 10.1155/2021/5567152
pmc: PMC8084681
doi:
Types de publication
Case Reports
Langues
eng
Pagination
5567152Informations de copyright
Copyright © 2021 Manuel Glauco Carbone et al.
Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest.
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