Seroprevalence of SARS-CoV-2 in Utsunomiya City, Greater Tokyo, after the first pandemic in 2020.
communicable diseases
coronavirus infections
seroepidemiologic studies
Journal
Journal of general and family medicine
ISSN: 2189-7948
Titre abrégé: J Gen Fam Med
Pays: Japan
ID NLM: 101689875
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
received:
10
08
2020
revised:
15
10
2020
accepted:
09
11
2020
entrez:
12
5
2021
pubmed:
13
5
2021
medline:
13
5
2021
Statut:
epublish
Résumé
A seroepidemiological study was conducted on a random sample of households in Utsunomiya City, Tochigi Prefecture, Greater Tokyo, Japan, to assess the seroprevalence of SARS-CoV-2. The level of IgG antibodies in the blood of the recruited subjects was assessed using chemiluminescence immunoassay analysis. In addition, the population-based prevalence of SARS-CoV-2 was estimated. Three positive afebrile cases were confirmed. The estimated unweighted prevalence and weighted prevalence of SARS-CoV-2 infection were 0.40% and 1.23%, respectively. This study suggests that the prevalence of SARS-CoV-2 may have been underestimated. Wider testing strategies may lead to revealing more SARS-CoV-2 cases.
Sections du résumé
BACKGROUND
BACKGROUND
A seroepidemiological study was conducted on a random sample of households in Utsunomiya City, Tochigi Prefecture, Greater Tokyo, Japan, to assess the seroprevalence of SARS-CoV-2.
METHODS
METHODS
The level of IgG antibodies in the blood of the recruited subjects was assessed using chemiluminescence immunoassay analysis. In addition, the population-based prevalence of SARS-CoV-2 was estimated.
RESULTS
RESULTS
Three positive afebrile cases were confirmed. The estimated unweighted prevalence and weighted prevalence of SARS-CoV-2 infection were 0.40% and 1.23%, respectively.
CONCLUSIONS
CONCLUSIONS
This study suggests that the prevalence of SARS-CoV-2 may have been underestimated. Wider testing strategies may lead to revealing more SARS-CoV-2 cases.
Identifiants
pubmed: 33977017
doi: 10.1002/jgf2.408
pii: JGF2408
pmc: PMC8090832
doi:
Types de publication
Journal Article
Langues
eng
Pagination
160-162Informations de copyright
© 2020 The Authors. Journal of General and Family Medicine published by John Wiley & Sons Australia, Ltd on behalf of Japan Primary Care Association.
Déclaration de conflit d'intérêts
Authors declare no conflict of interests for this article.
Références
Lancet. 2020 Feb 22;395(10224):542-545
pubmed: 32061313
Int J Infect Dis. 2020 May;94:49-52
pubmed: 32251798
N Engl J Med. 2020 May 28;382(22):2081-2090
pubmed: 32329971
JAMA. 2020 Jun 16;323(23):2425-2427
pubmed: 32421144