Quality of life of COVID-19 critically ill survivors after ICU discharge: 90 days follow-up.
15D instrument
Acute respiratory distress syndrome
COVID-19
Coronavirus
Health-related quality of life
Journal
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
ISSN: 1573-2649
Titre abrégé: Qual Life Res
Pays: Netherlands
ID NLM: 9210257
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
accepted:
28
04
2021
pubmed:
13
5
2021
medline:
6
10
2021
entrez:
12
5
2021
Statut:
ppublish
Résumé
The onset of the coronavirus disease 19 (COVID-19) pandemic in Italy induced a dramatic increase in the need for intensive care unit (ICU) beds for a large proportion of patients affected by COVID-19-related acute respiratory distress syndrome (ARDS). The aim of the present study was to describe the health-related quality of life (HRQoL) at 90 days after ICU discharge in a cohort of COVID-19 patients undergoing invasive mechanical ventilation and to compare it with an age and sex-matched sample from the general Italian and Finnish populations. Moreover, the possible associations between clinical, demographic, social factors, and HRQoL were investigated. COVID-19 ARDS survivors from 16 participating ICUs were followed up until 90 days after ICU discharge and the HRQoL was evaluated with the 15D instrument. A parallel cohort of age and sex-matched Italian population from the same geographic areas was interviewed and a third group of matched Finnish population was extracted from the Finnish 2011 National Health survey. A linear regression analysis was performed to evaluate potential associations between the evaluated factors and HRQoL. 205 patients answered to the questionnaire. HRQoL of the COVID-19 ARDS patients was significantly lower than the matched populations in both physical and mental dimensions. Age, sex, number of comorbidities, ARDS class, duration of invasive mechanical ventilation, and occupational status were found to be significant determinants of the 90 days HRQoL. Clinical severity at ICU admission was poorly correlated to HRQoL. COVID-19-related ARDS survivors at 90 days after ICU discharge present a significant reduction both on physical and psychological dimensions of HRQoL measured with the 15D instrument. NCT04411459.
Identifiants
pubmed: 33977415
doi: 10.1007/s11136-021-02865-7
pii: 10.1007/s11136-021-02865-7
pmc: PMC8113006
doi:
Banques de données
ClinicalTrials.gov
['NCT04411459']
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2805-2817Investigateurs
Marco Tartaglione
(M)
Valentina Chiarini
(V)
Virginia Buldini
(V)
Carlo Coniglio
(C)
Federico Moro
(F)
Clara Barbalace
(C)
Mario Citino
(M)
Nicola Cilloni
(N)
Lorenzo Giuntoli
(L)
Angela Bellocchio
(A)
Emanuele Matteo
(E)
Giacinto Pizzilli
(G)
Antonio Siniscalchi
(A)
Chiara Tartivita
(C)
Francesco Matteo
(F)
Annalisa Marchio
(A)
Igor Bacchilega
(I)
Laura Bernabé
(L)
Sonia Guarino
(S)
Elena Mosconi
(E)
Luca Bissoni
(L)
Lorenzo Viola
(L)
Emiliano Gamberini
(E)
Tommaso Meconi
(T)
Vittorio Pavoni
(V)
Aline Pagni
(A)
Patrizia Pompa Cleta
(PP)
Marco Cavagnino
(M)
Anna Malfatto
(A)
Angelina Adduci
(A)
Silvia Pareschi
(S)
Gabriele Melegari
(G)
Jessica Maccieri
(J)
Elisa Marinangeli
(E)
Fabrizio Racca
(F)
Marco Verri
(M)
Giulia Falò
(G)
Elisabetta Marangoni
(E)
Francesco Boni
(F)
Giulia Felloni
(G)
Federico Domenico Baccarini
(FD)
Marina Terzitta
(M)
Stefano Maitan
(S)
Maddalena Parise
(M)
Bernardo Bugiani
(B)
Francesca Masoni
(F)
Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer Nature Switzerland AG.
Références
Crit Care. 2012 Oct 26;16(5):R209
pubmed: 23098317
Dtsch Arztebl Int. 2017 Feb 17;114(7):103-109
pubmed: 28302253
Crit Care Resusc. 2006 Dec;8(4):302-8
pubmed: 17227266
JAMA. 2020 May 26;323(20):2052-2059
pubmed: 32320003
Crit Care. 2020 Apr 16;24(1):154
pubmed: 32299472
Lancet Respir Med. 2020 Jul;8(7):717-725
pubmed: 32422180
Intensive Care Med. 2020 Jul;46(7):1303-1325
pubmed: 32514598
Minerva Anestesiol. 2018 Sep;84(9):1024-1031
pubmed: 29338144
Lancet Respir Med. 2014 May;2(5):369-79
pubmed: 24815803
JAMA. 2020 Apr 28;323(16):1545-1546
pubmed: 32167538
Psychiatry Res. 2020 Jun;288:112954
pubmed: 32325383
Am J Phys Med Rehabil. 2020 Aug;99(8):669-673
pubmed: 32467492
Ann Med. 2001 Jul;33(5):328-36
pubmed: 11491191
J Int Neuropsychol Soc. 2004 Nov;10(7):1005-17
pubmed: 15803563
Crit Care. 2019 Nov 12;23(1):352
pubmed: 31718695
Curr Opin Crit Care. 2018 Feb;24(1):35-40
pubmed: 29189296
Crit Care. 2020 May 6;24(1):198
pubmed: 32375845
Am J Respir Crit Care Med. 2020 May 15;201(10):1299-1300
pubmed: 32228035
Am J Health Syst Pharm. 2015 Aug 1;72(15):1315-23
pubmed: 26195658
Ann Med. 2001 Jul;33(5):358-70
pubmed: 11491195
Respir Care. 2016 May;61(5):689-99
pubmed: 27121623
JAMA Intern Med. 2020 Oct 1;180(10):1345-1355
pubmed: 32667669
JAMA. 2020 Apr 28;323(16):1574-1581
pubmed: 32250385
Am J Respir Crit Care Med. 2001 May;163(6):1389-94
pubmed: 11371406
JAMA. 2002 Dec 11;288(22):2859-67
pubmed: 12472328
Crit Care. 2020 Jun 4;24(1):285
pubmed: 32498689
Crit Care Med. 2014 Feb;42(2):369-77
pubmed: 24158172
Intensive Care Med. 2020 Jun;46(6):1099-1102
pubmed: 32291463
EClinicalMedicine. 2020 Aug;25:100463
pubmed: 32838236
Crit Care. 2020 Aug 8;24(1):491
pubmed: 32771053
Intensive Care Med. 2016 May;42(5):725-738
pubmed: 27025938
Crit Care. 2018 Jan 18;22(1):8
pubmed: 29347987
Eur Ann Otorhinolaryngol Head Neck Dis. 2020 May;137(3):173-175
pubmed: 32332004
J Clin Exp Neuropsychol. 2015;37(6):641-52
pubmed: 26011761
Can J Neurol Sci. 2007 Nov;34(4):427-32
pubmed: 18062450
N Engl J Med. 2013 Oct 3;369(14):1306-16
pubmed: 24088092
Qual Life Res. 2015 Mar;24(3):599-606
pubmed: 25145637
Intensive Care Med. 2012 Oct;38(10):1573-82
pubmed: 22926653
N Engl J Med. 2011 Apr 7;364(14):1293-304
pubmed: 21470008
Chest. 2011 Jun;139(6):1340-1346
pubmed: 21330382
J Affect Disord. 2020 Nov 1;276:446-452
pubmed: 32871676
Crit Care. 2015 Aug 05;19:274
pubmed: 26242743
Anaesthesist. 2013 Apr;62(4):261-70
pubmed: 23558717
Breathe (Sheff). 2019 Jun;15(2):98-101
pubmed: 31191717
Crit Care Med. 2020 Sep;48(9):e799-e804
pubmed: 32452888
Intensive Care Med. 2000 Sep;26(9):1304-11
pubmed: 11089757
Physiol Behav. 2017 Jul 1;176:139-148
pubmed: 28363838
Thorax. 2017 Apr;72(4):311-317
pubmed: 27440140
Rev Bras Ter Intensiva. 2019 Oct-Dec;31(4):555-560
pubmed: 31967232
N Engl J Med. 2003 Feb 20;348(8):683-93
pubmed: 12594312
Med Intensiva (Engl Ed). 2020 Dec;44(9):583-585
pubmed: 32475608
PLoS One. 2018 Jun 25;13(6):e0199656
pubmed: 29940026
Am J Respir Crit Care Med. 2012 Jun 15;185(12):1307-15
pubmed: 22492988
Intensive Care Med. 2021 Jan;47(1):137-138
pubmed: 33037883
J Rehabil Med. 2020 Apr 15;52(4):jrm00044
pubmed: 32286675
Heart Lung. 2020 Nov - Dec;49(6):883-884
pubmed: 32690219
Eur Respir J. 2020 Jun 18;55(6):
pubmed: 32381497