Transplant of Elderly Patients: Is There an Upper Age Cutoff?

Aged Graft Survival Humans Kidney Transplantation Liver Diseases Liver Transplantation Tissue Donors Tissue and Organ Procurement
Age limit Elderly recipients Liver transplant Old donors

Journal

Clinics in liver disease
ISSN: 1557-8224
Titre abrégé: Clin Liver Dis
Pays: United States
ID NLM: 9710002

Informations de publication

Date de publication:
02 2021
Historique:
entrez: 12 5 2021
pubmed: 13 5 2021
medline: 26 10 2021
Statut: ppublish

Résumé

Increased life expectancy and advances in the care of chronic liver disease has increased the number of elderly patients needing liver transplant. Organ donation policies prioritize transplant to the sickest. There is an ongoing debate with regard to balancing the principles of equity and utility. Several hospitals have adopted center-specific policies and there has been an increased trend of transplant in elderly patients since 2002. Appropriate patient selection and long-term outcomes in the setting of limited organ availability pose several challenges. This article reviews the data and discusses the pros and cons of transplants in the elderly.

Identifiants

DOI: 10.1016/j.cld.2020.09.001 PMID: 33978580 PMC: PMC7577688
pubmed: 33978580
pii: S1089-3261(20)30079-9
doi: 10.1016/j.cld.2020.09.001
pmc: PMC7577688
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

209-227

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure C. Cottone and N.P. Polanco have nothing to disclose. K.R. Bhamidimarri receives research grants from Allergan, Gilead, Genfit, Mallinckrodt, Viking therapies, and Hepquant; participates in scientific advisory boards for Gilead, Abbvie, Mallinckrodt, and Intercept, and receives speaker honoraria from Alexion and Intercept.

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Auteurs

Claudia Cottone (C)

Department of Internal Medicine at Northwestern Medicine McHenry Hospital, Rosalind Franklin University of Medicine and Science, 4309 West Medical Center Drive, McHenry, IL 60050, USA. Electronic address: Claudia.cottone13@gmail.com.

Nathalie A Pena Polanco (NA)

Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Suite 1105, Miami, FL 33136, USA.

Kalyan Ram Bhamidimarri (KR)

Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Suite 1144, Miami, FL 33136, USA.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Transplant of Elderly Patients: Is There an...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunologie en transplantation › Réaction de l'hôte contre le greffon › Survie du greffon › Transplant of Elderly Patients: Is There an...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Transplant of Elderly Patients: Is There an...
questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures de chirurgie urogénitale › Procédures de chirurgie urologique › Transplantation rénale › Transplant of Elderly Patients: Is There an...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Transplant of Elderly Patients: Is There an...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation de tissu › Transplantation hépatique › Transplant of Elderly Patients: Is There an...
questionsmedicales.fr › Personnes › Donneurs de tissus › Transplant of Elderly Patients: Is There an...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Acquisition d'organes et de tissus › Transplant of Elderly Patients: Is There an...