Structure and Reactivity of N-Heterocyclic Alkynyl Hypervalent Iodine Reagents.

alkynyl transfer density functional calculations heterocycles hypervalent iodine sulfoximine

Journal

Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765
Titre abrégé: Chemistry
Pays: Germany
ID NLM: 9513783

Informations de publication

Date de publication:
26 Jul 2021
Historique:
received: 25 04 2021
pubmed: 13 5 2021
medline: 13 5 2021
entrez: 12 5 2021
Statut: ppublish

Résumé

Ethynylbenziodoxol(on)e (EBX) cyclic hypervalent iodine reagents have become popular reagents for the alkynylation of radicals and nucleophiles, but only offer limited possibilities for further structure and reactivity fine-tuning. Herein, the synthesis of new N-heterocyclic hypervalent iodine reagents with increased structural flexibility based on amide, amidine and sulfoximine scaffolds is reported. Solid-state structures of the reagents are reported and the analysis of the I-C

Identifiants

pubmed: 33978974
doi: 10.1002/chem.202101475
pmc: PMC8361724
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

10979-10986

Subventions

Organisme : Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
ID : 200020_182798
Organisme : Agence Nationale de la Recherche
ID : ANR-17-CE07-0048-01

Informations de copyright

© 2021 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.

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Auteurs

Eliott Le Du (E)

Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015, Lausanne, Switzerland.

Thibaut Duhail (T)

Institut Lavoisier de Versailles, Université Paris-Saclay, UVSQ, CNRS, UMR 8180, 7800, Versailles, France.

Matthew D Wodrich (MD)

Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015, Lausanne, Switzerland.

Rosario Scopelliti (R)

Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC GE, BCH 2111, 1015 Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015, Lausanne, Switzerland.

Farzaneh Fadaei-Tirani (F)

Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC GE, BCH 2111, 1015 Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015, Lausanne, Switzerland.

Elsa Anselmi (E)

Institut Lavoisier de Versailles, Université Paris-Saclay, UVSQ, CNRS, UMR 8180, 7800, Versailles, France.
Université de Tours, Faculté des Sciences et Techniques, 37200, Tours, France.

Emmanuel Magnier (E)

Institut Lavoisier de Versailles, Université Paris-Saclay, UVSQ, CNRS, UMR 8180, 7800, Versailles, France.

Jerome Waser (J)

Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015, Lausanne, Switzerland.

Classifications MeSH