Deletion of N-acetylmuramyl-L-alanine amidases alters the host immune response to
Ami1
Ami4
Mycobacterium tuberculosis
amidase
host–pathogen interaction
immunopathology
macrophage
mice
mutant
Journal
Virulence
ISSN: 2150-5608
Titre abrégé: Virulence
Pays: United States
ID NLM: 101531386
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
entrez:
13
5
2021
pubmed:
14
5
2021
medline:
17
12
2021
Statut:
ppublish
Résumé
Peptidoglycan (PG), a heteropolysaccharide component of the mycobacterial cell wall can be shed during tuberculosis infection with immunomodulatory consequences. As such, changes in PG structure are expected to have important implications on disease progression and host responses during infection with
Identifiants
pubmed: 33980132
doi: 10.1080/21505594.2021.1914448
pmc: PMC8128173
doi:
Substances chimiques
Cytokines
0
Peptidoglycan
0
Amidohydrolases
EC 3.5.-
Alanine
OF5P57N2ZX
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1227-1238Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
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